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1. Autoimmune Diseases

   For the phenomenon of autoimmune diseases, partial loss of immunological tolerance is key. The main disease is multiple sclerosis. It is still not...

   Wolfgang Walz in The Gliocentric Brain

   Chapter 2023
   

2. Autoimmune Diseases

   in Dictionary of Toxicology

   Reference work entry 2024
   

3. Exploring the relationship between infectious agents and autoimmune diseases: a review

   The relationship between infectious agents and autoimmune diseases is a complex issue. In recent years, increasing clinical cases have indicated that...

   Zhihui Feng, Xueli Yang, ... **anliang Hou in European Journal of Clinical Microbiology & Infectious Diseases

   Article 03 June 2024
   

4. Autoimmune diseases: targets, biology, and drug discovery

   Autoimmune diseases (AIDs) arise from a breakdown in immunological self-tolerance, wherein the adaptive immune system mistakenly attacks healthy...

   Shu-jie Li, Yan-li Wu, ... H. Eric Xu in Acta Pharmacologica Sinica

   Article 14 December 2023
   

5. Genetic map** across autoimmune diseases reveals shared associations and mechanisms

   Autoimmune and inflammatory diseases are polygenic disorders of the immune system. Many genomic loci harbor risk alleles for several diseases, but...

   Matthew R. Lincoln, Noah Connally, ... Chris Cotsapas in Nature Genetics

   Article 13 May 2024
   

6. Immunoinformatics for the Diagnosis and Monitoring of Autoimmune Diseases

   A complicated and diverse set of illnesses known as autoimmune diseases occur when the immune system attacks healthy cells and tissues, causing...

   Shalesh Gangwar, Neha Sharma, Devinder Toor in Concepts in Pharmaceutical Biotechnology and Drug Development

   Chapter 2024
   

7. Neoself Antigens Presented on MHC Class II Molecules in Autoimmune Diseases

   Major histocompatibility complex (MHC) class II molecules play a crucial role in immunity by presenting peptide antigens to helper T cells. Immune...

   Hui **, Hisashi Arase in Basic Immunology and Its Clinical Application

   Chapter 2024
   

8. HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases

   HMGB1, a nucleoprotein, is expressed in almost all eukaryotic cells. During cell activation and cell death, HMGB1 can function as an alarm protein...

   Wenxuan Ren, Lei Zhao, ... **aoguang Shi in Molecular Medicine

   Article Open access 04 September 2023
   

9. The oral microbiome in autoimmune diseases: friend or foe?

   The human body is colonized by abundant and diverse microorganisms, collectively known as the microbiome. The oral cavity has more than 700 species...

   **aoyan Huang, **angyu Huang, ... Shaohong Huang in Journal of Translational Medicine

   Article Open access 22 March 2023
   

10. Advances of autoimmune rheumatic diseases related to malignant tumors

    Background

    Malignant neoplasms are a well-recognized global public health concern, with significant impacts on human health and quality of life. The...

    Miaomiao Zhao, Liangyu Mi, ... Ke Xu in Inflammation Research

    Article Open access 28 September 2023

11. The role of the cGAS-STING signaling pathway in viral infections, inflammatory and autoimmune diseases

    Pattern recognition receptors are an essential part of the immune system, which detect pathogen-associated molecular patterns (PAMPs) and...

    Ming-ming Wang, Yue Zhao, ... Ting Li in Acta Pharmacologica Sinica

    Article 01 June 2024
    

12. Diverse functions of myeloid-derived suppressor cells in autoimmune diseases

    Since myeloid-derived suppressor cells (MDSCs) were found suppressing immune responses in cancer and other pathological conditions, subsequent...

    **n **ong, Yang Zhang, Yu Wen in Immunologic Research

    Article Open access 21 September 2023
    

13. Endosomal Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseases

    Nucleic acid (NA)-sensing Toll-like receptors (TLRs) reside in the endosomal compartment of innate immune cells, such as macrophages and dendritic...

    Kensuke Miyake, Takuma Shibata, ... Ryosuke Hiranuma in Basic Immunology and Its Clinical Application

    Chapter 2024
    

14. Large-scale genome-wide association studies reveal the genetic causal etiology between air pollutants and autoimmune diseases

    Background

    Epidemiological evidence links a close correlation between long-term exposure to air pollutants and autoimmune diseases, while the...

    Jie Wen, **gwei Zhang, ... Peng Luo in Journal of Translational Medicine

    Article Open access 29 April 2024
    

15. Molecular Engineering of Interleukin-2 for Enhanced Therapeutic Activity in Autoimmune Diseases

    The interleukin-2 (IL-2) cytokine plays a crucial role in regulating immune responses and maintaining immune homeostasis. Its immunosuppressive...

    Luke M. Tomasovic, Kathy Liu, ... Jamie B. Spangler in BioDrugs

    Article 24 November 2023
    

16. The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases

    The discovery of FOXP3 ⁺ regulatory T (T _reg ) cells as a distinct cell lineage with a central role in regulating immune responses provided a deeper...

    Tomokazu S. Sumida, Nardos T. Cheru, David A. Hafler in Nature Reviews Immunology

    Article 19 February 2024
    

17. Crucial Roles of RSAD2/viperin in Immunomodulation, Mitochondrial Metabolism and Autoimmune Diseases

    Autoimmune diseases are typically characterized by aberrant activation of immune system that leads to excessive inflammatory reactions and tissue...

    Siyan Chen, Jiani Ye, ... Chunyan Hua in Inflammation

    Article 23 June 2024
    

18. Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases

    Systemic autoimmune diseases are characterized by the failure of the immune system to differentiate self from non-self. These conditions are...

    Gustaf Wigerblad, Mariana J. Kaplan in Nature Reviews Immunology

    Article 18 October 2022
    

19. Gut Microbiota and Autoimmune Diseases: Mechanisms, Treatment, Challenges, and Future Recommendations

    Purpose of Review

    This review provides an overview of the role of dysbiosis (imbalanced gut microbiota) in the maintenance of host homeostasis and...

    Fatemah Sadeghpour Heravi in Current Clinical Microbiology Reports

    Article Open access 16 January 2024
    

20. ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery

    The AT-rich interaction domain (ARID) family of DNA-binding proteins is a group of transcription factors and chromatin regulators with a highly...

    Cheng-cen Guo, H. Eric Xu, **ong Ma in Acta Pharmacologica Sinica

    Article 24 July 2023