Search
Search Results
-
Bistable perception of ambiguous images: simple Arrhenius model
Watching an ambiguous image leads to the bistability of its perception, that randomly oscillates between two possible interpretations. The relevant...
-
Monoclonal Antibody Reagent Stability and Expiry Recommendation Combining Experimental Data with Mathematical Modeling
Monoclonal antibodies (mAbs) are widely used as critical reagents in analytical assays. While regulatory guidelines exist for stability monitoring of...
-
Exploration of Coumarin Derivative: Experimental and Computational Modeling for Dipole Moment Estimation and Thermal Sensing Application
The Optical properties of the FBTC (1-((4-((5-chlorobenzo[d]oxazol-2-ylthio)methyl)-1H-1,2,3-triazol-1-yl)methyl)-3H-benzo[f]chromen-3-one) molecule...
-
Substitutions on Saturated Carbon Atom
The theory of reaction mechanisms is explained in more details on the examples of nucleophilic and radical substitutions on the saturated carbon...
-
Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants
PurposeIntroduction of the activation energy (E a ) as a kinetic parameter to describe and discriminate monoclonal antibody (mAb) stability.
...
-
Microwave ablation trocar for ablating cancerous tumors: a numerical analysis
Microwave ablation (MWA) is a newly develo** minimally invasive thermal therapies technology. The ablation region obtained during MWA mainly...
-
Methods to Measure Water Permeability
Water permeability is a key feature of the cell plasma membranes, and it has seminal importance for several cell functions such as cell volume...
-
-
Preformulation of 3D Printable Pharmaceutical Dosage Forms
Preformulation studies are designed to ensure a pharmaceutical dosage form will be produced within the best scenario of materials and processing...
-
Hot-Melt Extrusion: a Roadmap for Product Development
Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include...
-
Synthesis, Structural and Fluorescence Investigations of Novel Li2Ba5W3O15:Sm3+ Phosphors for Photonic Device Applications
In the current study, Sm 3+ ions doped Lithium Barium Tungstate (Li 2 Ba 5 W 3 O 15 ) (LBW) phosphors with the ability to emit orange-red light were made...
-
Protein Adsorption at a Gas-Aqueous Interface
This chapter will introduce fundamental aspects of molecular adsorption of proteins to a fluid-fluid interface. The focus of the chapter will be on...
-
A phenomenological model of pulsatile blood pressure-affected degradation of polylactic acid (PLA) vascular stent
The stent implantation may alter the post-operative patient’s blood pressure, and bioresorbable vascular stents (BVS) as a candidate to treat...
-
Excipients: Characterization, Purpose, and Selection
Protein drugs are subject to chemical, conformational, and colloidal instability throughout the manufacturing process through fill/finish to the...
-
Delayed Luminescence as a Tool to Study the Structures of Systems of Biological Interest and Their Collective Long-Living Excited States
In the last few decades, the description of the biological world has been based on a pervasive mechanistic approach. Even if this point of view has...
-
Physico-chemistry and Cytotoxicity of Tenofovir-Loaded Acid Phosphatase-Responsive Chitosan Nanoparticles
This study assesses the in vitro release of tenofovir (TFV)-loaded triphosphate ( TPP ) cross-linked chitosan nanoparticles (NPs) catalyzed by human...
-
Antibodies: A History of Their Discovery and Properties
This is the story of how the antibody molecules of the immune system were discovered. The early beginnings on immunity were phenomenological,...
-
Formulation of Biologics Including Biopharmaceutical Considerations
This chapter describes the various issues a formulator of biologics faces when turning an active pharmaceutical ingredient (API) into a...
-
Solvent-Assisted Secondary Drying of Spray-Dried Polymers
PurposeThe purpose of this work is to introduce solvent-assisted secondary drying, a method used to accelerate the residual solvent removal from...
-
Naphthalene and its Derivatives: Efficient Fluorescence Probes for Detecting and Imaging Purposes
Naphthalene, white crystalline solid having polycyclic aromatic hydrocarbon with characteristic mothball order is naturally present in crucial oils...
