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Angiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis
Spondyloarthritis (SpA) is a chronic inflammatory disease that results in bone ankylosis. The tissue renin-angiotensin system (RAS) is an emerging...
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Impact of calcium channel blockers and angiotensin receptor blockers on hematological parameters in type 2 diabetic patients
Antihypertensive medications have been associated with a reduction in hemoglobin (Hb) levels, leading to clinically significant anemia. We aimed to...
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Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients
BackgroundRenin–angiotensin–aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting...
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Sacubitril/valsartan compared to equivalent/sub-equivalent dose angiotensin receptor blocker or angiotensin-converting enzyme inhibitor in heart failure with reduced ejection fraction: a meta-analysis of randomized trials
PurposeThe objective of this meta-analysis is to determine how sacubitril/valsartan (SV) compares to equivalent and sub-equivalent angiotensin...
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The Renin-Angiotensin System and Cancer
The renin-angiotensin system (RAS), classically known for its role in cardiovascular homeostasis, is increasingly recognized to be dysregulated in...
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Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission
The brain renin-angiotensin system (RAS) has been related to dopaminergic degeneration, and high expression of the angiotensin II (AngII) type 1...
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Renin-Angiotensin System in Hematological Malignancies
The regular functioning of the human body is the result of interactions between numerous organs and biological systems, with the Renin-Angiotensin...
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Renin–Angiotensin–Aldosterone System as an Old New Target in Heart Failure Therapy
The prevalence of heart failureHeart failure (HF) increases worldwide. Long-term maladaptive activation of the renin–angiotensin–aldosterone...
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Renin Angiotensin System in Aging and Regeneration
Age is an independent risk factor for develo** various diseases related to the cardiovascular system, kidney, nervous system, diabetesDiabetes etc....
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Prognostic impact of angiotensin-converting enzyme inhibitors and angiotensin receptors blockers in esophageal or gastric cancer patients with hypertension - a real-world study
BackgroundAngiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are used in treating cardiovascular diseases....
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Understanding the Renin-Angiotensin System in Coronavirus Disease 2019
At the beginning of the COVID-19 pandemic, there was increasing concern that therapy with renin-angiotensin-system (RAS) inhibitors, such as...
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The role of the brain renin-angiotensin system in Parkinson´s disease
The renin-angiotensin system (RAS) was classically considered a circulating hormonal system that regulates blood pressure. However, different tissues...
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Valsartan: An Angiotensin Receptor Blocker Modulates BDNF Expression and Provides Neuroprotection Against Cerebral Ischemic Reperfusion Injury
AT1 receptor blockers (ARBs) are commonly used drugs to treat cardiovascular disease and hypertension, but research on their impact on brain...
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H2S Signals and Renin Angiotensin System in Cardiovascular Diseases
Hydrogen sulfideHydrogen sulfide (H2S) is recently recognized as the third gasotransmitter alongside with nitric oxide and carbon monoxide. H2S...
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Cardiovascular Protective Arm of Renin Angiotensin System
Cardiovascular protective axis of Renin Angiotensin SystemRenin angiotensin system is relatively newer concept and largely originated from the...
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Renin-Angiotensin System and Cancer: From Laboratory to Clinics
Renin-Angiotensin System (RAS) is a vital system regulating blood pressure and maintaining sodium homeostasis in the human body. It consists of...
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Renin Angiotensin System Inhibitors in Heart Failure with Reduced Ejection Fraction: Clinical Evidence and Considerations for Use
The renin angiotensin systemRenin angiotensin system (RAS) plays an important role in the regulation of body fluids and blood pressure. Therapy with...
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Renin Angiotensin System Activity in Different Cancers: Mechanistic Insight and Preclinical Studies
The Renin Angiotensin System (RAS) is maintain arterial blood pressure as well as fluid and electrolyte balance in human body. In recent there...
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Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation
Insulin resistance is a major contributor to the pathogenesis of several human diseases, including type 2 diabetes, hypertension, and hyperlipidemia....
