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Changes in Adhesion and the Expression of Adhesion Molecules in PBMCs after Aneurysmal Subarachnoid Hemorrhage: Relation to Cerebral Vasospasm
Aneurysmal subarachnoid hemorrhage (aSAH) is a neurovascular disease produced by extravasation of blood to the subarachnoid space after rupture of...
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A systematic review and meta-analysis of circulating adhesion molecules in rheumatoid arthritis
BackgroundThe availability of robust biomarkers of endothelial activation might enhance the identification of subclinical atherosclerosis in...
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Regulation of Presynaptic Release Machinery by Cell Adhesion Molecules
The synapse is a highly specialized asymmetric structure that transmits and stores information in the brain. The size of pre- and postsynaptic...
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Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
BackgroundAbout 30% of Prostate cancer (PCa) patients progress to metastatic PCa that remains largely incurable. This evidence underlines the need...
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The interaction between adhesion protein 33 (TvAP33) and BNIP3 mediates the adhesion and pathogenicity of Trichomonas vaginalis to host cells
BackgroundTrichomonas vaginalis is a widespread and important sexually transmitted pathogen. Adherence to the surface of the host cell is the...
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Integrative analysis of cell adhesion molecules in glioblastoma identified prostaglandin F2 receptor inhibitor (PTGFRN) as an essential gene
BackgroundGlioblastoma (GBM) is the most common primary malignant brain tumor in adults exhibiting infiltration into surrounding tissues, recurrence,...
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Quantifying Adhesion of Inflammatory Cells to the Endothelium In Vitro
We present a simple and quantitative assay system that accurately models human endothelium by use of primary human umbilical vein endothelial cells...
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Nectins and Nectin-like molecules drive vascular development and barrier function
Angiogenesis, barriergenesis, and immune cell migration are all key physiological events that are dependent on the functional characteristics of the...
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Ex Vivo Perfusion System to Analyze Chemokine-Driven Leukocyte Adhesion
At the moment, many researchers are using in vitro techniques to investigate chemokine-driven leukocyte adhesion/recruitment, for example, by using a...
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Bacterial Adhesion, Virulence, and Biofilm Formation
The adhesion of bacteria to implanted biomaterial and human tissue surfaces is the first and essential step in the pathogenesis of infection....
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Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions
BackgroundNeovascular age-related macular degeneration (nAMD) is a major cause of blindness in the elderly. The disease is due to the growth of...
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Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β
BackgroundCell adhesion is indispensable for appropriate tissue architecture and function in multicellular organisms. Besides maintaining tissue...
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JNK inhibition enhances cell–cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes
c-Jun NH 2 -terminal protein kinase (JNK) and p38 are stress-activated mitogen-activated protein kinases (MAPK) that are phosphorylated by various...
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miR-27a inhibits molecular adhesion between monocytes and human umbilical vein endothelial cells; systemic approach
ObjectiveThe endothelial cells overexpress the adhesion molecules in the leukocyte diapedesis pathway, develo** vessel subendothelial molecular...
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Antibiofilm activity of marine microbial natural products: potential peptide- and polyketide-derived molecules from marine microbes toward targeting biofilm-forming pathogens
Controlling and treating biofilm-related infections is challenging because of the widespread presence of multidrug-resistant microbes. Biofilm, a...
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The Impact of MicroRNAs in Cell Adhesion and Tumour Angiogenesis
MicroRNAs (miRNAs) are a class of non-coding RNAs of roughly 22 nt length that plays a salient and myriad role in gene expression and regulation....
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Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells
Background3D culture is increasingly used in cancer research, as it allows the growth of cells in an environment that mimics in vivo conditions....
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Extracellular Matrix and Adhesion Molecules
In this chapter, students will learn about the main components of the extracellular matrix (ECM) – a complex meshwork of fibers and ground substance...
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A Multiscale Model for Shear-Mediated Platelet Adhesion Dynamics: Correlating In Silico with In Vitro Results
Platelet adhesion to blood vessel walls is a key initial event in thrombus formation in both vascular disease processes and prosthetic cardiovascular...
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Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing
Vγ9Vδ2 T cells are specialized effector cells that have gained prominence as immunotherapy agents due to their ability to target and kill cells with...
