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Structural Characterization of Food Allergens by Nuclear Magnetic Resonance Spectroscopy
As allergies, especially those triggered by food, are becoming more and more prevalent, it is of increasing importance to fully understand the...
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Magnetic Resonance Spectroscopy (MRS) in Alzheimer’s Disease
MRS is a noninvasive technique to measure different metabolites in the brain. Changes in the levels of certain metabolites can be used as surrogate...
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Serum metabolomics profiling by proton nuclear magnetic resonance spectroscopy reveals sexual dimorphism and masculinization of intermediate metabolism in women with polycystic ovary syndrome (PCOS)
BackgroundThe polycystic ovary syndrome (PCOS) is associated with insulin resistance, obesity and cardiometabolic comorbidities. We here challenged...
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Metabolomics Analysis of Complex Biological Specimens Using Nuclear Magnetic Resonance Spectroscopy
Metabolomics is an emerging technology that promises the extensive analyses of small molecules in the biological specimen. Metabolomics is recognized...
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Process Monitoring and Characterization for Extraction of Herbal Medicines Based on Proton (1H) Nuclear Magnetic Resonance Spectroscopy and Multivariate Batch Modeling: a Case Study
PurposeThe control of batch-to-batch quality variations remains a challenging task for herbal medicine (HM) pharmaceutics. In this study, a novel...
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Advanced Magnetic Resonance Imaging (MRI) of Brain
Magnetic Resonance Imaging (MRI) uses the principle of nuclear magnetic resonance to generate high-resolution images of brain. Due to abundance of...
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1H magnetic resonance spectroscopic imaging of deuterated glucose and of neurotransmitter metabolism at 7 T in the human brain
Impaired glucose metabolism in the brain has been linked to several neurological disorders. Positron emission tomography and carbon-13 magnetic...
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Analysis of Carbohydrates by Nuclear Magnetic Resonance Spectroscopy
NMR spectroscopy has shown to be extremely useful for the characterization of glycan structures. Carbohydrates have two natural NMR-active nuclei: 1H...
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Analysis of the Adsorbed Vaccine Formulations Using Water Proton Nuclear Magnetic Resonance—Comparison with Optical Analytics
PurposeTo evaluate w NMR, an emerging noninvasive analytical technology, for characterizing aluminum-adjuvanted vaccine formulations.
Methods ...
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A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS
Energy metabolism is fundamental for life. It encompasses the utilization of carbohydrates, lipids, and proteins for internal processes, while...
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Nuclear Magnetic Resonance Spectroscopy
Nuclear magnetic resonance (NMR) spectroscopy is usually combined with infrared (IR) spectroscopy for the complete analysis of the structure of an...
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Serum metabolomics profiling by proton nuclear magnetic resonance spectrometry of the response to single oral macronutrient challenges in women with polycystic ovary syndrome (PCOS) compared with male and female controls
BackgroundThe polycystic ovary syndrome (PCOS) is associated with insulin resistance, obesity and cardiometabolic comorbidities. We here challenged...
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Neurobiochemistry Alterations Associated with Major Depression: A Review of Translational Magnetic Resonance Spectroscopic Studies
Conventional magnetic resonance imaging uses water resonance to generate images of brain tissue. Here, we describe how a spectrum of potentially...
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Application of NMR Spectroscopy in Viral Assembly Characterization
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique widely utilized for small molecule and biomolecule characterization in both...
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In vivo detection of dysregulated choline metabolism in paclitaxel-resistant ovarian cancers with proton magnetic resonance spectroscopy
BackgroundChemoresistance gradually develops during treatment of epithelial ovarian cancer (EOC). Metabolic alterations, especially in vivo easily...
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Exceptionally rare IDH1-mutant adult medulloblastoma with concurrent GNAS mutation revealed by in vivo magnetic resonance spectroscopy and deep sequencing
Medulloblastoma (MB) is the most common malignant brain tumor occurring in childhood and rarely found in adults. Based on transcriptome profile, MB...
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Potential of Magnetic Resonance (MR) Methods in Clinical Cancer Research
Magnetic resonance imaging (MRI) is often used as a versatile imaging modality for diagnosis of various diseases in clinical medicine. The technique...
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Investigating the neurochemistry of the human visual system using magnetic resonance spectroscopy
Biochemical processes underpin the structure and function of the visual cortex, yet our understanding of the fundamental neurochemistry of the visual...
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A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging
Hepatobiliary magnetic resonance imaging (MRI) can inform the diagnosis of liver tumours in patients with liver cirrhosis and hepatitis. However, its...
