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Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid
RationaleAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and restricted/stereotyped...
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Group-by-Treatment Interaction Effects in Comparative Bioavailability Studies
Comparative bioavailability studies often involve multiple groups of subjects for a variety of reasons, such as clinical capacity limitations. This...
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Subty** of Group 3/4 medulloblastoma as a potential prognostic biomarker among patients treated with reduced dose of craniospinal irradiation: a Japanese Pediatric Molecular Neuro-Oncology Group study
BackgroundOne of the most significant challenges in patients with medulloblastoma is reducing the dose of craniospinal irradiation (CSI) to minimize...
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The ESCMID Study Group for Clostridioides difficile: History, Role, and Perspectives
Clostridioides difficile (C. difficile) is a major nosocomial pathogen but is also increasingly recognised as an important diarrhoeal pathogen in the...
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The trimethoxyphenyl (TMP) functional group: a versatile pharmacophore
The Trimethoxyphenyl (TMP) group serves as a pharmacophore in numerous potent agents exhibiting diverse bioactivity effects. This moiety is...
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Group XIV C-type lectins: emerging targets in tumor angiogenesis
C-type lectins, distinguished by a C-type lectin binding domain (CTLD), are an evolutionarily conserved superfamily of glycoproteins that are...
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Gastrointestinal stromal tumour (GIST): British Sarcoma Group clinical practice guidelines
BackgroundBritish Sarcoma Group guidelines for the management of GIST were initially informed by those published by the European Society of Clinical...
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Progress towards a glycoconjugate vaccine against Group A Streptococcus
The Group A Carbohydrate (GAC) is a defining feature of Group A Streptococcus (Strep A) or Streptococcus pyogenes . It is a conserved and simple...
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Diversity of group 1 innate lymphoid cells in human tissues
Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing lymphocytes lacking antigen-specific receptors, which include...
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Group-specific cellular metabolism in Medulloblastoma
BackgroundCancer metabolism influences multiple aspects of tumorigenesis and causes diversity across malignancies. Although comprehensive research...
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An automated group-housed oral fentanyl self-administration method in mice
Rationale and objectivesSocial factors play a critical role in human drug addiction, and humans often consume drugs together with their peers. In...
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A Potential Source of Bias in Group-Level EEG Microstate Analysis
Microstate analysis is a promising technique for analyzing high-density electroencephalographic data, but there are multiple questions about...
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High Mobility Group Box Protein (HMGB1): A Potential Therapeutic Target for Diabetic Encephalopathy
HMGB (high mobility group B) is one of the ubiquitous non-histone nuclear protein superfamilies that make up the HMG (high mobility group) protein...
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Unlocking Team Dynamics: Exploring the Influence of Group Regulation on Technical Development in Small-Sided Soccer Games
PurposeDiscussions held by players during the halftime of a soccer match are widely recognized as influential factors in boosting their involvement...
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Design, synthesis and antitumor activity evaluation of pyrimidine derivatives containing 4-hydroxypiperidine group
In the current study, a series of pyrimidine derivatives containing the 4-hydroxypiperidine group were designed and synthesized, and the...
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MYC up-regulation confers vulnerability to dual inhibition of CDK12 and CDK13 in high-risk Group 3 medulloblastoma
BackgroundMedulloblastoma (MB) is the most common cerebellar malignancy during childhood. Among MB, MYC-amplified Group 3 tumors display the worst...
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Evaluation of the frequency of ABO and Rh-Hr blood-group systems in different acquired cataracts type
ObjectivesThis study evaluated the relationship between acquired cataract’s different types and the ABO and Rh blood classes.
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Global economic burden per episode for multiple diseases caused by group A Streptococcus
Considering the lack of existing evidence on economic burden for diseases caused by group A Streptococcus , we estimated the economic burden per...
