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Duplication of SOX3 in an SRY-negative 46,XX male with prostatic utricle: case report and literature review
Background46,XX male disorders of sex development are rare. Approximately 80% of cases of testicular tissue differentiation may be due to...
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Clinical application of serum tumor abnormal protein in prostate cancer patients
PurposeTo explore the clinical value of tumor abnormal protein (TAP) in the diagnosis and prognosis evaluation of prostate cancer.
Methods ...
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The Relationship between the Premenstrual Syndrome and Resting Cardiac Vagal Tone in Young Healthy Females: Role of Hormonal Contraception
Evolutionary-based predictions imply that the premenstrual syndrome (PMS) affects women who failed to conceive while in biosocial conditions that...
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Sexual Differentiation of the Brain and Behavior: A Primer
A general theory of sexual differentiation of the brain derives from classic experiments performed in the twentieth century, which determined that...
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Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production
BackgroundIdiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure (ICP), impaired vision, and...
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Embryology in DSD
Embryological variations leading to DSD can be classified into problems relating to sex determination, testicular development or hormonal signalling...
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Increased proliferation and neuronal fate in prairie vole brain progenitor cells cultured in vitro: effects by social exposure and sexual dimorphism
BackgroundThe prairie vole ( Microtus ochrogaster ) is a socially monogamous rodent that establishes an enduring pair bond after cohabitation, with...
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Acute, but not repeated, cocaine exposure alters allopregnanolone levels in the midbrain of male and female rats
RationaleMultiple psychiatric disorders are associated with altered brain and serum levels of neuroactive steroids, including the endogenous...
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Protective effect of didymin against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced reproductive toxicity in male rats
Purpose2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) is one of the most potent environmental toxicants, which causes oxidative stress and adversely...
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Report from the BfR expert hearing on practicability of hormonal measurements: recommendations for experimental design of toxicological studies with integrated hormonal end points
This publication summarizes discussions that were held during an international expert hearing organized by the German Federal Institute for Risk...
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Neuroprotective Effect of Vitamin D on Behavioral and Oxidative Parameters of Male and Female Adult Wistar Rats Exposed to Mancozeb (manganese/zinc ethylene bis-dithiocarbamate)
The constant exposure of rural workers to pesticides is a serious public health problem. Mancozeb (MZ) is a pesticide linked to hormonal,...
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Prenatal Amphetamine-Induced Dopaminergic Alteration in a Gender- and Estrogen-Dependent Manner
Prenatal exposure to amphetamine induces changes in dopamine receptors in mesolimbic areas and alters locomotor response to amphetamine during...
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The developmental origins of sex-biased expression in cardiac development
BackgroundExpression patterns between males and females vary in every adult tissue, even in organs with no conspicuous dimorphisms such as the heart....
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Sex hormones, aging and cardiometabolic syndrome
It is well documented that the metabolic syndrome predisposes patients to increased cardiovascular risk. Emerging data indicates that cardiovascular...
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Resilience of females to acute blood–brain barrier damage and anxiety behavior following mild blast traumatic brain injury
Low-level blast exposure can result in neurological impairment for military personnel. Currently, there is a lack of experimental data using sex as a...
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Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women
Fatty liver disease (FLD) caused by metabolic dysfunction is the leading cause of liver disease and the prevalence is rising, especially in women....
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A clinicopathological study about the epidemiology of granulosa cell tumors in Lebanon
BackgroundGranulosa Cell Tumors (GCT) are considered the most frequent type of sex-cord stromal tumors. These tumors constitute 3-6% of neoplasms of...
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Cardiorespiratory response to exercise in endurance-trained premenopausal and postmenopausal females
PurposeTo assess the influence of different hormonal profiles on the cardiorespiratory response to exercise in endurance-trained females.
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Velocity loss is a flawed method for monitoring and prescribing resistance training volume with a free-weight back squat exercise
PurposeThe aim of this study was to examine the goodness of fit, prediction accuracy, and stability of general and individual relationships between...
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Sexual Incentive Motivation
Motivation can be described as the processes that activate, direct, and determine the persistence of goal-directed behavior. A certain level of...