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Microbial active functional modules derived from network analysis and metabolic interactions decipher the complex microbiome assembly in mangrove sediments
BackgroundThe metabolic interactions of microbes significantly affect the assembly of microbial communities that play important roles in...
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Structural characterization of SLYM—a 4th meningeal membrane
Traditionally, the meninges are described as 3 distinct layers, dura, arachnoid and pia. Yet, the classification of the connective meningeal...
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The influence of the environment and lifestyle on myopia
BackgroundMyopia, commonly known as near-sightedness, has emerged as a global epidemic, impacting almost one in three individuals across the world....
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A brief history of the Feulgen reaction
One hundred years ago, Robert Feulgen published a landmark paper in which he described the first method to stain DNA in cells and tissues. Although a...
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Brain Energy and Metabolism
All the processes described in this textbook require energy. Ample clinical evidence indicates that the brain is exquisitely sensitive to...
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Disinfection exhibits systematic impacts on the drinking water microbiome
Limiting microbial growth during drinking water distribution is achieved either by maintaining a disinfectant residual or through nutrient limitation...
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Multifaceted roles of flavonoids mediating plant-microbe interactions
Plant-microbe interactions dynamically affect plant growth, health, and development. The mechanisms underpinning these associations are—to a large...
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Decoding populations in the ocean microbiome
Understanding the characteristics and structure of populations is fundamental to comprehending ecosystem processes and evolutionary adaptations....
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Organelle-specific localization of glutathione in plants grown under different light intensities and spectra
Plant ascorbate and glutathione metabolism counteracts oxidative stress mediated, for example, by excess light. In this review, we discuss the...
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Genetic diversity analysis of Dermacentor nuttalli within Inner Mongolia, China
BackgroundTicks (Arthropoda, Ixodida), after mosquitoes, are the second most prevalent vector of infectious diseases. They are responsible for...
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From Operating Table to Laboratory Bench: The Path Toward Metastasis Research from the Clinical Setting
Presence of metastasis translates unequivocally into worse prognosis for our patients. Translational medicine has been our response to offer patients...
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Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning
A plaque assay—the gold-standard method for measuring the concentration of replication-competent lytic virions—requires staining and usually more...
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Does climate change increase the risk of marine toxins? Insights from changing seawater conditions
Marine toxins produced by marine organisms threaten human health and impose a heavy public health burden on coastal countries. Lately, there has been...
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Mass Cytometry for the Characterization of Individual Cell Types in Ovarian Solid Tumors
Mass cytometry aka Cytometry by Time-Of-Flight (CyTOF) is one of several recently developed multiparametric single-cell technologies designed to...
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Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer
BackgroundNon-small cell lung cancer (NSCLC) remains a leading cause of cancer-related deaths worldwide, primarily due to its propensity for...
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Immune modulation in malignant pleural effusion: from microenvironment to therapeutic implications
Immune microenvironment and immunotherapy have become the focus and frontier of tumor research, and the immune checkpoint inhibitors has provided...
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Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction
BackgroundThe autophagy adapter SQSTM1/p62 is crucial for maintaining homeostasis in various organs and cells due to its protein–protein interaction...
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Biodegradable AuNP-Based Plasmonic Nanogels as Contrast Agents for Computed Tomography and Photoacoustics
Gold nanoparticles (AuNP) are well-established contrast agents in computed tomography (CT) and photoacoustic imaging (PAI). A wide variety of AuNP...
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Genetic Diversity and Fine-Scale Population Structure Analysis of the Placocheilus cryptonemus in the Nujiang River from mtDNA and Microsatellite Markers
AbstractThe Nujiang River is rich in aquatic biodiversity, especially endemic fish. However, long-term human interference, such as cascade hydropower...
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Teriflunomide as a therapeutic means for myelin repair
BackgroundPromotion of myelin repair in the context of demyelinating diseases such as multiple sclerosis (MS) still represents a clinical unmet need,...
