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Targeting oral tumor microenvironment for effective therapy
Oral cancers are among the common head and neck malignancies. Different anticancer therapy modalities such as chemotherapy, immunotherapy, radiation...
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A Conformal Medical Antenna Based on a Flexible Substrate
The results of studies of a conformal broadband applicator antenna for microwave radiothermometry based on a flexible substrate and textile...
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Animal Model-Based Studies to Evaluate the Lipid-Based Drug Delivery Nanocarriers for Cancer Treatment
In an effort to find products and processes for human healthcare, experimental objects and materials that can simulate the human body have been used...
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Computational Tools for Cancer Nanomedicine
Computational tools in cancer nanomedicine consist of many approaches that enable progress at the convergence of computer engineering and medical...
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The role of neoadjuvant radiochemotherapy in the management of localized high-grade soft tissue sarcoma
BackgroundStandard treatment of soft tissue sarcoma (STS) of the extremities includes limb-sparing surgery combined with pre- or postoperative...
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Protective effect of dihydromyricetin on hyperthermia-induced apoptosis in human myelomonocytic lymphoma cells
Dihydromyricetin (DMY) is a traditional herbal medicine, with a wide range of biological activities. Extreme hyperthermia (HT) can suppress the...
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Mining local exome and HLA data to characterize pharmacogenetic variants in Saudi Arabia
Pharmacogenomics (PGx) is a promising field of precision medicine where efficacy of drugs is maximized while side effects are minimized for...
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Nanotechnology in Cancer Diagnosis and Therapy
Earliest precise diagnosis and targeted therapy underlines the efficiency of successful cancer management. Conventional diagnostics are usually...
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Nanotechnology in Cancer Diagnosis and Therapy
Earliest precise diagnosis and targeted therapy underlines the efficiency of successful cancer management. Conventional diagnostics are usually...
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Study on the thermal stability of nab-paclitaxel during hyperthermic intraperitoneal chemotherapy
BackgroundAlbumin-bound paclitaxel (nab-paclitaxel), as a special targeted preparation of paclitaxel, has the advantages of good curative effect and...
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Theranostics Nanomaterials for Safe Cancer Treatment
The current advancement in diagnostic research by implementing nanotechnology encourages researchers worldwide to focus towards new possibilities of...
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Plasmonic Photothermal Therapy (PPTT) of Cancer
The generation of electromagnetic field within and around the dissipative nanostructures upon light radiation on them is closely associated with the...
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Architecture of Cancer Therapies
In this chapter, we will discuss that the classical therapy of solid cancers is surgery, which is often combined with radiation therapy and cytotoxic...
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CRISPR/Cas9-Editing-Based Modeling of Tumor Hypoxia
One of the critical characteristics of solid tumors is hypoxia, which has been linked to a poor prognosis for cancer patients. Solid tumors...
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Extrachromosomal circular DNA (eccDNA): an emerging star in cancer
Extrachromosomal circular DNA (eccDNA) is defined as a type of circular DNA that exists widely in nature and is independent of chromosomes. EccDNA...
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Plasmonic Photothermal Therapy (PPTT) of Cancer
The generation of electromagnetic field within and around the dissipative nanostructures upon light radiation on them is closely associated with the...
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PKPD Modeling and Dosing Considerations in Advanced Ovarian Cancer Patients Treated with Cisplatin-Based Intraoperative Intraperitoneal Chemotherapy
Intraperitoneal chemoperfusion (IPEC) of cisplatin is a popular treatment for advanced ovarian cancer, typically under hyperthermia (HIPEC). The use...
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Development of nano-immunotherapy for cancer treatment: achievements and scopes
BackgroundCancer immunotherapy, which activates the immune system of the human body to fight cancer cells, is a new paradigm for cancer treatment...
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Exome sequencing in undiagnosed congenital myopathy reveals new genes and refines genes–phenotypes correlations
BackgroundCongenital myopathies are severe genetic diseases with a strong impact on patient autonomy and often on survival. A large number of...
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Applications of Nanotechnology in Converging the Biomarker Science for Advancement in Cancer Detection and Treatment
Cancer biomarkers with high selectivity, specificity, and reproducibility assume fundamental task in diagnosis, prognosis, and prediction of therapy...