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Tissue Engineering for Sciatic Nerve Repair: Review of Methods and Challenges
PurposeThe primary objective of this study was to offer a thorough examination of the various tissue engineering approaches employed in sciatic nerve...
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Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody
BackgroundThe blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor...
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Review of Machine Learning Techniques in Soft Tissue Biomechanics and Biomaterials
Background and ObjectiveAdvanced material models and material characterization of soft biological tissues play an essential role in pre-surgical...
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Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria
The complex gastrointestinal environment and the intestinal epithelial barrier constrain the design and effectiveness of orally administered tumour...
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Applications of Nanoscaffolds in Tissue Engineering
Purpose of ReviewConsistently, a huge number of surgeries are performed to supplant tissue which is damaged through infection or injury. The emerging...
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3D printing titanium grid scaffold facilitates osteogenesis in mandibular segmental defects
Bone fusion of defect broken ends is the basis of the functional reconstruction of critical maxillofacial segmental bone defects. However, the...
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Modulation of microglial polarization by sequential targeting surface-engineered exosomes improves therapy for ischemic stroke
Microglia are important cells that act on regulating neuroinflammation and neurofunction after the induction of ischemic stroke (IS). Consequently,...
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Biomaterials for Tissue Engineering Applications and Current Updates in the Field: A Comprehensive Review
Tissue engineering has emerged as an interesting field nowadays; it focuses on accelerating the auto-healing mechanism of tissues rather than organ...
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Biodegradable and Biocompatible 3D Constructs for Dental Applications: Manufacturing Options and Perspectives
Designing 3D constructs with appropriate materials and structural frameworks for complex dental restorative/regenerative procedures has always...
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Introduction to 3D Cell Culture
This chapter explains the importance of 3D cell culture and highlights its potential and benefits in comparison to traditional 2D cultivation. Since... -
Surface Modification of Tissue Engineering Scaffolds
Scaffolds in tissue engineering provide a substrate for cells to grow on, in order to form functional, organised tissue. The ideal scaffold thus... -
Newly developed 3D in vitro models to study tumor–immune interaction
Immunotherapy as a rapidly develo** therapeutic approach has revolutionized cancer treatment and revitalized the field of tumor immunology...
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Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert
Modern radiotherapy techniques have advanced and become more sophisticated. End-to-end 3D verification of the complex radiotherapy dose distribution...
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High-Speed All-Optical Neural Interfaces with 3D Temporally Focused Holography
Understanding brain function requires technologies that can monitor and manipulate neural activity with cellular resolution and millisecond precision... -
Engineering and Characterization of a Biomimetic Microchip for Differentiating Mouse Adipocytes in a 3D Microenvironment
Although two-dimensional (2D) cell cultures are the standard in cell research, one pivotal disadvantage is the lack of cell–cell and...
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Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to address defects arising from trauma, inefficient wound...
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Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes
Mutations in the α-Synuclein (αS) gene promote αS monomer aggregation that causes neurodegeneration in familial Parkinson’s disease (fPD). However,...
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Tissue Chips: Contemporary Applications and Advancements
The tissue chip is an efficient and highly applicable novel product developed by the amalgamation of cell biology, engineering and biomaterial... -
Modelling skeletal pain harnessing tissue engineering
Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is...
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Biomaterials-enabled electrical stimulation for tissue healing and regeneration
The electrical microenvironment is considered a pivotal determinant in various pathophysiological processes, including tissue homeostasis and wound...