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Showing 81-100 of 5,878 results
  1. Tissue Engineering for Sciatic Nerve Repair: Review of Methods and Challenges

    Purpose

    The primary objective of this study was to offer a thorough examination of the various tissue engineering approaches employed in sciatic nerve...

    Yasaman Ebrahimi-kia, Parivash Davoudi, Sima Bordbar in Journal of Medical and Biological Engineering
    Article 27 October 2023
  2. Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody

    Background

    The blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor...

    Thomas J. Esparza, Shiran Su, ... David L. Brody in Fluids and Barriers of the CNS
    Article Open access 24 August 2023
  3. Review of Machine Learning Techniques in Soft Tissue Biomechanics and Biomaterials

    Background and Objective

    Advanced material models and material characterization of soft biological tissues play an essential role in pre-surgical...

    Samir Donmazov, Eda Nur Saruhan, ... Senol Piskin in Cardiovascular Engineering and Technology
    Article 02 July 2024
  4. Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria

    The complex gastrointestinal environment and the intestinal epithelial barrier constrain the design and effectiveness of orally administered tumour...

    Yale Yue, Jiaqi Xu, ... Guangjun Nie in Nature Biomedical Engineering
    Article 02 May 2022
  5. Applications of Nanoscaffolds in Tissue Engineering

    Purpose of Review

    Consistently, a huge number of surgeries are performed to supplant tissue which is damaged through infection or injury. The emerging...

    B. Deepika, A. Gopikrishna, ... Koyeli Girigoswami in Current Pharmacology Reports
    Article 06 April 2022
  6. 3D printing titanium grid scaffold facilitates osteogenesis in mandibular segmental defects

    Bone fusion of defect broken ends is the basis of the functional reconstruction of critical maxillofacial segmental bone defects. However, the...

    Yongfeng Li, Huawei Liu, ... Min Hu in npj Regenerative Medicine
    Article Open access 24 July 2023
  7. Modulation of microglial polarization by sequential targeting surface-engineered exosomes improves therapy for ischemic stroke

    Microglia are important cells that act on regulating neuroinflammation and neurofunction after the induction of ischemic stroke (IS). Consequently,...

    **ntong Liu, Yunni Hao, ... Liang Zhao in Drug Delivery and Translational Research
    Article 16 August 2023
  8. Biomaterials for Tissue Engineering Applications and Current Updates in the Field: A Comprehensive Review

    Tissue engineering has emerged as an interesting field nowadays; it focuses on accelerating the auto-healing mechanism of tissues rather than organ...

    Alaa Emad Eldeeb, Salwa Salah, Nermeen A. Elkasabgy in AAPS PharmSciTech
    Article Open access 26 September 2022
  9. Biodegradable and Biocompatible 3D Constructs for Dental Applications: Manufacturing Options and Perspectives

    Designing 3D constructs with appropriate materials and structural frameworks for complex dental restorative/regenerative procedures has always...

    Deepika Sharma, Vijay Prakash Mathur, Bhabani K. Satapathy in Annals of Biomedical Engineering
    Article 27 July 2021
  10. Introduction to 3D Cell Culture

    This chapter explains the importance of 3D cell culture and highlights its potential and benefits in comparison to traditional 2D cultivation. Since...
    Dominik Egger, Sabrina Nebel in Basic Concepts on 3D Cell Culture
    Chapter 2021
  11. Surface Modification of Tissue Engineering Scaffolds

    Scaffolds in tissue engineering provide a substrate for cells to grow on, in order to form functional, organised tissue. The ideal scaffold thus...
    Zuyong Wang, Feng Wen, Mark Seow Khoon Chong in Polymeric Biomaterials for Tissue Regeneration
    Chapter 2023
  12. Newly developed 3D in vitro models to study tumor–immune interaction

    Immunotherapy as a rapidly develo** therapeutic approach has revolutionized cancer treatment and revitalized the field of tumor immunology...

    Peiyuan Mu, Shujuan Zhou, ... Zhen Zhang in Journal of Experimental & Clinical Cancer Research
    Article Open access 04 April 2023
  13. Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert

    Modern radiotherapy techniques have advanced and become more sophisticated. End-to-end 3D verification of the complex radiotherapy dose distribution...

    Muhammad Zamir Mohyedin, Hafiz Mohd Zin, ... Ahmad Taufek Abdul Rahman in Physical and Engineering Sciences in Medicine
    Article 18 April 2024
  14. High-Speed All-Optical Neural Interfaces with 3D Temporally Focused Holography

    Understanding brain function requires technologies that can monitor and manipulate neural activity with cellular resolution and millisecond precision...
    Ian Antón Oldenburg, Hayley Anne Bounds, Nicolas C. Pégard in All-Optical Methods to Study Neuronal Function
    Protocol Open access 2023
  15. Engineering and Characterization of a Biomimetic Microchip for Differentiating Mouse Adipocytes in a 3D Microenvironment

    Although two-dimensional (2D) cell cultures are the standard in cell research, one pivotal disadvantage is the lack of cell–cell and...

    Yu-ting Chen, Latha Ramalingam, ... Wei Li in Pharmaceutical Research
    Article 15 February 2022
  16. Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

    Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to address defects arising from trauma, inefficient wound...

    Katherine H. Griffin, Shierly W. Fok, J. Kent Leach in npj Regenerative Medicine
    Article Open access 09 December 2022
  17. Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes

    Mutations in the α-Synuclein (αS) gene promote αS monomer aggregation that causes neurodegeneration in familial Parkinson’s disease (fPD). However,...

    Silke Nuber, **aoqun Zhang, ... Dennis J. Selkoe in npj Parkinson's Disease
    Article Open access 29 February 2024
  18. Tissue Chips: Contemporary Applications and Advancements

    The tissue chip is an efficient and highly applicable novel product developed by the amalgamation of cell biology, engineering and biomaterial...
    Taranjot Kaur, Jigyasa Sharma, Seemha Rai in Biomedical Translational Research
    Chapter 2022
  19. Modelling skeletal pain harnessing tissue engineering

    Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is...

    Lucia Iafrate, Maria Cristina Benedetti, ... Gianluca Cidonio in In vitro models
    Article Open access 04 August 2022
  20. Biomaterials-enabled electrical stimulation for tissue healing and regeneration

    The electrical microenvironment is considered a pivotal determinant in various pathophysiological processes, including tissue homeostasis and wound...

    Han-Sem Kim, Tanza Baby, ... Hae-Won Kim in Med-X
    Article Open access 21 May 2024
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