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Acebutolol. Beta-adrenoceptor blocking drug, with limited cardioselectivity. Uses, side effects, etc. as for PRO-PRANOLOL. -
Chemotherapeutic Targets in Pneumocystis carinii
P. carinii pneumonia, the most common life-threatening infection in patients with the acquired immunodeficiency syndrome (AIDS)... -
Chemotherapy
Chemotherapeutic agents are intended to eliminate a foreign organism, or abnormal cells, from healthy tissues of the patient. An essential property... -
Antiparasitic Agents from Plants
Parasites are generally grouped into one of three broad classes: protozoa (single-celled organisms), helminths (including nematodes, trematodes, and... -
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Pharmacokinetics of halofantrine and n-desbutylhalofantrine in patients with falciparum malaria following a multiple dose regimen of halofantrine
Halofantrine is a new blood schizontocidal drug used for the treatment of multidrug-resistant falciparum malaria. The pharmacokinetics of...
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Pyrimethamin-resistantPlasmodium falciparum lack cross-resistance to methotrexate and 2,4-diamino-5-(substituted benzyl) pyrimidines
Methotrexate resistance induced in cultured Plasmodium falciparum depends on an altered dihydrofolate reductase with decreased affinity for...
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Malaria prophylaxis in travellers to tropical Africa
This study investigated travellers to tropical Africa with regard to prophylactic treatment of malaria. A total of 5703 travellers completed a...
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Stage-specific gametocytocidal effect in vitro of the antimalaria drug qinghaosu onPlasmodium falciparum
Qinghaosu, an anti-malaria drug, has been found to kill not only asexual blood stages but also the early stages of gametocytes of Plasmodium falciparum ...
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Plasmodium falciparum Infection and the Other Human Malarias
The arthropod-borne protozoan parasitoses caused by Plasmodium sp have produced incalculable human misery, morbidity, and mortality since antiquity;... -
Chemotherapy
Chemotherapeutic agents are intended to eliminate a foreign organism, or abnormal cells, from healthy tissues of the patient. An essential property... -
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Some Parasitoses Involving the Central Nervous System
This chapter deals with the various parasitoses of the central nervous system (CNS) in order of taxonomic classification (Table 8.1). When viewed in... -
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Antimalarial activity of new floxacrine-related acridinedione derivatives: studies on blood schizontocidal action of potential candidates againstP. berghei in mice andP. falciparum in vivo and in vitro
Deoxyfloxacrine derivatives (1-hydrazone: S 83 0083; 1-imine: S 84 7277) and floxacrine derivatives (10-methoxy-floxacrine: L 84 7667; 1-imine: L 84...
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Resistance to Sulfonamides
Sulfonamides were the first widely used selective antibacterial drugs, and the report of G. Domagk in 1935 on the efficacy of prontosil in...