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Exosomal-miRNas expression and growth factors released by mononuclear cells of CLAD patients in response to extracorporeal photopheresis
BackgroundCLAD (Chronic Lung Allograft Dysfunction) remains a serious complication following lung transplantation. Some evidence shows that portions...
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Epigenetic and metabolic reprogramming in inflammatory bowel diseases: diagnostic and prognostic biomarkers in colorectal cancer
Background and aim"Inflammatory bowel disease" (IBD) is a chronic, relapsing inflammatory disease of the intestinal tract that typically begins at a...
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MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model
BackgroundPrevious studies have confirmed that the microglial activation and subsequent inflammatory responses in the trigeminal nucleus caudalis...
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miR-451a was selectively sorted into exosomes and promoted the progression of esophageal squamous cell carcinoma through CAB39
Exosomes are emerging mediators of cell-cell communication, which are secreted from cells and may be delivered into recipient cells in cell...
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Melatonin Alters the miRNA Transcriptome of Inflammasome Activation in Murine Microglial Cells
Systemic inflammation can have devastating effects on the central nervous system via its resident immune cells, the microglia. One of the primary...
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Oxygen–Glucose Deprived Peripheral Blood Mononuclear Cells Protect Against Ischemic Stroke
Stroke is the leading cause of severe long-term disability. Cell therapy has recently emerged as an approach to facilitate functional recovery in...
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Expression of Circulating Rennin—Angiotensin—Aldosterone-Related microRNAs in Patients with Thyrotoxic Heart Disease
Thyrotoxic heart disease (THD) is a common and severe complication of hyperthyroidism and the etiology of this complication remains poorly...
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MicroRNA-125b as a valuable predictive marker for outcome after autologous hematopoietic stem cell transplantation
BackgroundRelapse is a frequent occurrence in autologous hematopoietic stem cell transplantation (AHSCT), and early relapse after AHSCT results in...
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Crosstalk Between miRNA and Protein Expression Profiles in Nitrate-Exposed Brain Cells
Growing evidence reported a strong association between the nitrate ingestion and adverse health consequences in humans, including its detrimental...
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Eight weeks of combined exercise training do not alter circulating microRNAs-29a, -133a, -133b, and -155 in young, healthy men
PurposeIndividuals with a family history of type 2 diabetes (FH +) have an increased risk of develo** type 2 diabetes. Circulating microRNAs...
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Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway
Sonic Hedgehog (Shh) signaling cascade is one of the complex signaling pathways that control the accurately organized developmental processes in...
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Candidate MicroRNA Biomarkers in Lupus Nephritis: A Meta-analysis of Profiling Studies in Kidney, Blood and Urine Samples
ContextLupus nephritis (LN) is a kidney disease caused by systemic lupus erythematosus in which kidneys are attacked by the immune system. So far,...
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Identification and Validation of Lipid Metabolism Gene FASN-Associated miRNA in Wilms Tumor
miRNA has been a research hotspot in recent years and its scope of action is very wide, involving the regulation of cell proliferation,...
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Systematic review of circulating MICRORNAS as biomarkers of cervical carcinogenesis
BackgroundCervical cancer is a preventable disease, but it is a major public health problem despite having a good prognosis when diagnosed early....
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Design and Fabrication of a DNA-copper Nanocluster-based Biosensor for Multiple Detections of Circulating miRNAs in Early Screening of Breast Cancer
Breast cancer is one of the most prevalent cancers and a significant cause of fatalities in women. Diagnosis of breast cancer faces substantial...
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Decoding the role of inflammation-related microRNAs in cancer cachexia: a study using HPV16-transgenic mice and in silico approaches
Cachexia is associated with poor prognosis in cancer patients, and inflammation is one of its main drive factors. MicroRNAs have recently emerged as...
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The emerging role non-coding RNAs in B cell-related disorders
Long non-coding RNAs and microRNAs have recently attained much attention regarding their role in the development of B cell lineage as well as...
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MicroRNA: Crucial modulator in purinergic signalling involved diseases
Both microRNAs (miRNAs) and purinergic signalling are widely and respectively expressed in various tissues of different organisms and play vital...
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NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase
Vascular smooth muscle cells (VSMCs) play an important role in maintaining vascular function. Inflammation-mediated VSMC dysfunction leads to...
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Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal and aggressive malignancies with a 5-year survival rate less than 9%. Early...
