Search
Search Results
-
Qualitative and semi-quantitative ultrasound assessment in delta and Omicron Covid-19 patients: data from high volume reference center
Objective: to evaluate the efficacy of US, both qualitatively and semi-quantitatively, in the selection of treatment for the Covid-19 patient, using...
-
Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study
BackgroundLynch Syndrome (LS) is an inherited cancer predisposition syndrome defined by pathogenic variants in the mismatch repair (MMR) or EPCAM ...
-
A clinical available decision support scheme for optimizing prostate biopsy based on mpMRI
BackgroundCombined MRI/Ultrasound fusion targeted biopsy (TBx) and systematic biopsy (SBx) results in better prostate cancer (PCa) detection relative...
-
Multi-omics and immune cells’ profiling of COVID-19 patients for ICU admission prediction: in silico analysis and an integrated machine learning-based approach in the framework of Predictive, Preventive, and Personalized Medicine
BackgroundIntensive care unit admission (ICUA) triage has been urgent need for solving the shortage of ICU beds, during the coronavirus disease 2019...
-
Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England
BackgroundThe faecal immunochemical test (FIT) was introduced to triage patients with low-risk symptoms of possible colorectal cancer in English...
-
Relationship between tracheal intubation and the drugs used by patients with drug overdose due to self-harm
BackgroundTracheal intubation may be performed in patients with drug overdose due to self-harm; however, the details of the causative drug are...
-
Integrated fever management: disease severity markers to triage children with malaria and non-malarial febrile illness
Febrile symptoms in children are a leading cause of health-care seeking behaviour worldwide. The majority of febrile illnesses are uncomplicated and...
-
HPV testing in Polish population-based cervical cancer screening programme (HIPPO project)—study protocol of a randomised healthcare policy trial
BackgroundAn Organised Cervical Cancer Screening Programme (OCCSP) was started in Poland in 2006/2007. Each woman aged 25 to 59 is eligible for a...
-
Performance of DNA methylation analysis in the detection of high-grade cervical intraepithelial neoplasia or worse (CIN3+): a cross-sectional study
It is commonly accepted that host genes show high methylation in cervical intraepithelial neoplasia 3 (CIN3) or worse (CIN3+). However, study quality...
-
Diagnosis of Childhood Tuberculosis in Low- and Middle-Income Countries
Pediatric tuberculosis (TB) is one of the neglectedDiseaseneglected groups globally. Non-specific symptomsSymptom, the paucibacillary nature of the... -
Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank
BackgroundProstate cancer is highly heritable, with >250 common variants associated in genome-wide association studies. It commonly presents with...
-
Cervical screening: ESGO-EFC position paper of the European Society of Gynaecologic Oncology (ESGO) and the European Federation of Colposcopy (EFC)
This paper summarises the position of ESGO and EFC on cervical screening based on existing guidelines and opinions of a team of lead experts. HPV...
-
Scoring for Hemorrhage Severity in Traumatic Injury
Severity scores have long been used for the classification or stratification of patients for clinical care and in the evaluation of outcomes. Such... -
Novel concepts in cervical cancer screening: a comparison of VIA, HPV DNA test and p16INK4a/Ki-67 dual stain cytology in Western Kenya
BackgroundScreening of unvaccinated women remains essential to mitigate the high morbidity/mortality of cervical cancer. Here, we compared visual...
-
The value of cytokine levels in triage and risk prediction for women with persistent high-risk human papilloma virus infection of the cervix
BackgroundCervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The...
-
Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients
The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical manifestations. Most patients develop moderate clinical...
-
-
Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis
BackgroundCervical carcinogenesis is mediated by the HPV-E6 and E7 oncoproteins, considered as biomarkers usable in managing screen-positive women.
... -
Multimorbidity in persons with non-traumatic spinal cord injury and its impact on healthcare utilization and health outcomes
Study designCross-sectional survey in Canada.
ObjectivesTo explore multimorbidity (the coexistence of two/more health conditions) in persons with...
-
The performance of single and combination test strategies using visual inspection, cytology, high-risk HPV DNA and HPV16/18 to screen South African women with and without HIV-infection
BackgroundCervical cancer screening strategies should ideally be informed by population-specific data. Strategies recommended for secondary...