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Occurrence and determinants of seizures and their impact on tuberculous meningitis: a prospective evaluation
ObjectiveTo assess the incidence of seizures and the factors contributing to poor outcomes in patients with tuberculous meningitis (TBM).
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Heterozygous and homozygous variants in STX1A cause a neurodevelopmental disorder with or without epilepsy
The neuronal SNARE complex drives synaptic vesicle exocytosis. Therefore, one of its core proteins syntaxin 1A (STX1A) has long been suspected to...
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Genes Involved in Pharmacoresistant Epilepsy
This chapter is devoted to drug-resistant epilepsy and its genetic mechanisms. There are currently six hypotheses proposed for pharmacoresistant...
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Age-Dependency of Levetiracetam Effects on Exocytotic GABA Release from Nerve Terminals in the Hippocampus and Cortex in Norm and After Perinatal Hypoxia
Perinatal hypoxia can lead to multiple chronic neurological deficits, e.g., mental retardation, behavioral abnormalities, and epilepsy. Levetiracetam...
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Psychological and Psychiatric Aspects of Brain and Spinal Cord Tumors
Central nervous systemCentral nervous system (CNS) (CNS) tumors are mainly diagnosed by physical symptoms such as paralysis, visual fieldVisual field...
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A review of the potential neurological adverse events of COVID-19 vaccines
Despite the advantages of getting access to the coronavirus disease 2019 (COVID-19) vaccines, their potential ability to induce severe adverse events...
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Hot-Melt Extrusion Paired Fused Deposition Modeling 3D Printing: Development of Pharmaceutical Medications
In recent years much research has been conducted exploring the suitability of various additive manufacturing (AM) techniques for develo**...
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The Neurovascular Unit Dysfunction in the Molecular Mechanisms of Epileptogenesis and Targeted Therapy
Epilepsy is a multifaceted neurological syndrome characterized by recurrent, spontaneous, and synchronous seizures. The pathogenesis of epilepsy,...
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Epilepsy and ASM Formulations
Epilepsy, characterized by abnormalities in neuronal activity, remains a challenge for a significant proportion of patients despite the increasing...
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Incidence, characteristics, and risk factors of drug-associated muscle adverse reaction: a retrospective real-world study of inpatients
ObjectiveTo analyze the clinical characteristics, incidence, and distribution of drug-associated muscle adverse reactions (DAMAR) in real-world...
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Identifying subcortical connectivity during brain tumor surgery: a multimodal study
Bipolar direct electrical stimulation (DES) of an awake patient is the reference technique for identifying brain structures to achieve maximal safe...
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Effect of Antiepileptics on Sleep
This chapter focuses on discussing the effect of antiepileptic drugs on sleep to better understand the treatment effect, especially in patients of...
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The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy
Targeted tissue ablation involving the anterior hippocampus is the standard of care for patients with drug-resistant mesial temporal lobe epilepsy....
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Opsoclonus-Myoclonus-Ataxia Syndrome Due to Covid-19
Opsoclonus-myoclonus syndrome (OMS) as a rare neurological encephalopathic entity associated with non-specific infections or cancer processes has...
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CNS Glutamate in Impulsive Aggression
Glutamate appears to be a critical neurotransmitter in the neurocircuitry and neurophysiology of aggressive behaviors in mammals including humans....