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Viren sind auch Schmarotzer, sogar die allerschmarotzerhaftesten
Falls der Leser die Lektüre bis hierher durchgehalten hat, kann er sich die logische Frage stellen, was genau die Viren in diesem Buch zu suchen...
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Evolving etiologies, comorbidities, survival, and costs of care in adult encephalitis
Encephalitis is a central nervous system disorder, often caused by infectious agents or aberrant immune responses. We investigated causes,...
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Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype
Variants in MAGT1 have been identified as the cause of an immune deficiency termed X-linked immunodeficiency with magnesium defect, Epstein-Barr...
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Biology of Astrocytes in CNS Infection
There is an increasing interest in the central role of astrocytes in CNS injury and disease. They react to injury by the increased expression of a...
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Microorganisms in Pathogenesis and Management of Scleroderma (Systemic Sclerosis)
As environmental triggers, microorganisms are considered largely involved in the multifactorial pathogenetic scenario of autoimmune diseases....
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Viruses in glioblastoma: an update on evidence and clinical trials
BackgroundGlioblastoma (GB) is a lethal and aggressive brain tumour. While molecular characteristics of GB is studied extensively, the aetiology of...
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The Value of Cell-Free Circulating DNA Profiling in Patients with Skin Diseases
Liquid biopsy, also known as fluid biopsy or fluid-phase biopsy, is the sampling and analysis of the blood, cerebrospinal fluid, saliva, pleural...
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HrpA anchors meningococci to the dynein motor and affects the balance between apoptosis and pyroptosis
BackgroundIn Neisseria meningitidis the HrpA/HrpB two-partner secretion system (TPS) was implicated in diverse functions including meningococcal...
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Pathogenesis of Viral Infections and Male Reproductive Health: An Evidence-Based Study
Viruses, being intracellular obligate parasites, can cause several congenital and sexually transmitted diseases. Depending on the site of infection,...
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New insights into pathogenesis point to HIV-1 Tat as a key vaccine target
Despite over 30 years of enormous effort and progress in the field, no preventative and/or therapeutic vaccines against human immunodeficiency virus...
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Quantitative Assay of SARS-CoV-2 RNA and Level of Proinflammatory Protein Gene Transcripts in Peripheral Blood Leukocytes after a Novel Coronavirus Infection
The possibility of finding persistent SARS-CoV-2 viral particles in human peripheral blood leukocytes after a novel coronavirus infection was shown....
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Human herpesvirus type 2 infection of primary murine astrocytes causes disruption of the mitochondrial network and remodeling of the actin cytoskeleton: an in vitro morphological study
Herpesviruses are capable of infecting not only neurons, where they establish latent infection, but also astrocytes. Since astrocytes are important...
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The Role of Chronic Infection in Alzheimer’s Disease: Instigators, Co-conspirators, or Bystanders?
Purpose of ReviewHerein, we provide a critical review of the clinical and translational research examining the relationship between viral and...
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A Novel 2-dimensional Multiplex qPCR Assay for Single-Tube Detection of Nine Human Herpesviruses
Human herpesviruses are double-stranded DNA viruses that are classified into nine species. More than 90% of adults are ever infected with one or more...
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Human parvovirus B19 infection in malignant and benign tissue specimens of different head and neck anatomical subsites
BackgroundThe role of human parvovirus B19 (B19V) infection in malignant and benign lesions such as head and neck squamous cell carcinomas (HNSCCs)...
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Oncogenic Virus-Induced Oxidative Stress and Epigenetic Regulation: An Insight into Host DNA Methylation
Stress response pathways alter the pathophysiological state of an organism that can culminate into oxidative stress by accumulation of reactive...
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Oncogenic Virus-Induced Oxidative Stress and Epigenetic Regulation: An Insight into Host DNA Methylation
Stress response pathways alter the pathophysiological state of an organism that can culminate into oxidative stress by accumulation of reactive...
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Mechanisms and consequences of mRNA destabilization during viral infections
During viral infection there is dynamic interplay between the virus and the host to regulate gene expression. In many cases, the host induces the...
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Multidimensional Roles of Microglial Cells in Neuroviral Infections
Microglial cells are the brain resident macrophages which are involved in maintaining CNS homeostasis. During CNS infections, the microglial cells...
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The Parasitism and Tumors Carcinogenesis: A Review Subject
BackgroundMulti-factorial reasons are an induction to cause cancer. Different infections and infestations with viruses, bacteria, and parasites have...
