Search
Search Results
-
-
Age-Related Features of the Response of the Liver and Stem Cells during Modeling of Liver Cirrhosis
We studied the age-related characteristics of the response of stem cells and liver in male Wistar rats to administration of carbon tetrachloride (CCl 4 ...
-
Diethylnitrosamine Induction of Hepatocarcinogenesis in Mice
Diethylnitrosamine (DEN) is a chemical hepatocarcinogenic agent that triggers a large array of oncogenic mutations after a single injection....
-
-
The protective effects of protocatechuic acid against natural and chemical toxicants: cellular and molecular mechanisms
Protocatechuic acid (PCA) is a water-soluble polyphenol compound that is extracted from certain fruits and plants or obtained from glucose...
-
Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice
The liver has a high regenerative ability and can induce spontaneous regression of fibrosis when early liver damage occurs; however, these abilities...
-
Inducibility of Metabolizing Enzymes
An important toxicologically relevant feature associated with foreign compound metabolism is the inducibility of metabolizing enzymes. Some...
-
S100A6 Activates Kupffer Cells via the p-P38 and p-JNK Pathways to Induce Inflammation, Mononuclear/macrophage Infiltration Sterile Liver Injury in Mice
Noninfectious liver injury, including the effects of chemical material, drugs and diet, is a major cause of liver diseases worldwide. In chemical and...
-
The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review
Besides synthetic drugs, a wide variety of medicinal plants have been used for the prevention and management of various liver disorders. Generally,...
-
Coffee, adenosine, and the liver
A variety of observational studies have demonstrated that coffee, likely acting through caffeine, improves health outcomes in patients with chronic...
-
Therapeutic Potential of MicroRNAs and Their Nanoparticle-based Delivery in the Treatment of Liver Fibrosis
Chronic liver disease is a global health problem owing to its high morbidity and the limited available treatment options. Liver fibrosis, the most...
-
Electron Attachment to Isolated Molecules as a Probe to Understand Mitochondrial Reductive Processes
This chapter describes the complementary experimental techniques Electron Transmission SpectroscopyElectron transmission spectroscopy (ETS) and...
-
Glycyrrhizae Radix et Rhizoma (Gan Cao) for the Management of COVID-19
This chapter introduces the therapeutic application of Glycyrrhizae Radix et Rhizoma for the management of coronavirus disease 2019 (COVID-19)....
-
Thiourea Catalysts for Synthesis of Active Pharmaceutical Ingredients
Thiourea is an important building block found in several drug molecules such as thioacetazone, enzalutamide, and thiocarlide. Thiourea derivatives...
-
Biological Activities of Some Edible Mushrooms
Since ancient times, mushrooms have been a valuable food source and traditional medicine worldwide. Edible mushrooms possess high nutritional value...
-
β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of NOX4
Hepatic fibrosis is a disease characterized by excessive deposition of extracellular matrix (ECM) in the liver. Activation of hepatic stellate cells...
-
Gadd45 in Senescence
Gadd45a, Gadd45b, and Gadd45g have been implicated in cell cycle arrest, DNA repair, apoptosis, innate immunity, genomic stability, and more recently...
-
Impact of Antibiotic Resistance of Bacteria in Biofilms and Microbial Fuel Cell: Confronting the Dark Box for Global Health Threat
Increased population activities, a growing market for animal nutrition, and extensive usage of antibiotics were responsible for the continued...
-
Cichorium intybus L.
Chicory (Cichorium intybus L.) is a biennial plant belonging to the Asteraceae (compositae) family. It has a woody character with a height reaching...