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Evidence of anti-inflammatory activity of Schizandrin A in animal models of acute inflammation
Schisandrin A (Sch A) is a lignin extracted from the fruit of Schisandra chinensis , which has potential anti-inflammatory properties and is used for...
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Immunpathologische Prozesse in der Übersicht
Immer, wenn das Immunsystem auffällig wird, handelt es sich um überschießende oder insuffiziente Effektorfunktionen. Meist ist dabei die Regulation...
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Anti-inflammatory Activity of Mesenchymal Stem Cells in λ-Carrageenan-Induced Chronic Inflammation in Rats: Reactions of the Blood System, Leukocyte-Monocyte Ratio
The variety of chronic diseases caused by a chronic inflammatory process is an unresolved problem in developed countries. Due to this, modern...
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Inflammatory Mediators, Nociceptors, and Their Interactions in Pain
Inflammation produces pro-inflammatory mediators for the induction of pain. These mediators include inflammatory cytokines and chemokines, lipids,...
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Increased Inflammation and Treatment of Depression: From Resistance to Reuse, Repurposing, and Redesign
Based on mounting clinical and translational evidence demonstrating the impact of exogenously administered inflammatory stimuli on the brain and...
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Memantine and Ibuprofen pretreatment exerts anti-inflammatory effect against streptozotocin-induced astroglial inflammation via modulation of NMDA receptor-associated downstream calcium ion signaling
AbstractWe had previously reported that neuroinflammation and memory impairment associated with intracerebroventricular streptozotocin (ICV STZ)...
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Prevention of Pro-inflammatory Markers By Medicinal Mushrooms Under Stressful Environment
Hypoxia and inflammation are vicious cycles and often difficult to point out which signal activates first, and often these signals reinforce in a...
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Inflammation and Pain
Inflammation is the body’s natural response to injury or the infiltration of a foreign substance. The process is defined by five cardinal signs:...
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Exploration of anti-inflammatory mechanism of forsythiaside A and forsythiaside B in CuSO4-induced inflammation in zebrafish by metabolomic and proteomic analyses
BackgroundInflammation is a general pathological phenomenon during severe disturbances to the homeostasis. Forsythiaside A (FA) and forsythiaside B...
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Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice
Despite intense efforts to develop efficient therapeutic regimes for asthma, there is a large demand for novel treatment strategies in this disease....
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Recent Development in Chronic Inflammation Research and Mangroves as Potential Source of Anti-inflammatory Agents
The chronic inflammatory processes are considered as important factors in the development and progression of micro- as well as macro-vascular...
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CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
Aging is a natural process associated with chronic inflammation in the development of vascular dysfunction. We hypothesized that chemokine C-C motif...
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Co-delivery of indomethacin and uricase as a new strategy for inflammatory diseases associated with high uric acid
Uric acid is the final metabolite in humans. High level of uric acid chronically induces urate deposition, aggravates kidney damage, and...
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Therapeutic potential of natural products in inflammation: underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives
Chronic inflammation is a common underlying factor in many major diseases, including heart disease, diabetes, cancer, and autoimmune disorders, and...
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Procyanidin alleviates ferroptosis and inflammation of LPS-induced RAW264.7 cell via the Nrf2/HO-1 pathway
Inflammation is a common occurrence in many medical conditions and is a natural defense mechanism of the human body. Ferroptosis, an iron-dependent...
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Melatonin Attenuates Imiquimod-Induced Psoriasis-Like Inflammation and Restores the Th17/Treg Immune Balance
Psoriasis is a common immune-mediated skin disease characterized by abnormally reactive inflammation and epidermal hyperplasia. Previous studies have...
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CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation through NF-κB signaling pathway in ankylosing spondylitis in vitro
BackgroundAnkylosing spondylitis (AS) is an autoimmune disease with a genetic correlation and is characterized by inflammation in the axial skeleton...
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Ameliorative effects of Atriplex crassifolia (C.A.Mey) on pain and inflammation through modulation of inflammatory biomarkers and GC–MS-based metabolite profiling
Atriplex crassifolia (A. crassifolia) is a locally occurring member of Chenopodiaceae family that has been used in folk medicine for the treatment of...
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Effective protection of photoreceptors using an inflammation-responsive hydrogel to attenuate outer retinal degeneration
Retinitis pigmentosa (RP) is an outer retinal degenerative disease that can lead to photoreceptor cell death and profound vision loss. Although...
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Immune Homeostasis Maintenance Through Advanced Immune Therapeutics to Target Atherosclerosis
Atherosclerosis remains the leading cause of coronary heart disease (CHD) with enormous health and societal tolls. Traditional drug development...