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Sex Differences in Vascular Function
Sex is an important biological variable that impacts several organism functions at the genetic, molecular, and cellular levels. Sex differences are... -
Extracellular matrix: the critical contributor to skeletal muscle regeneration—a comprehensive review
The regenerative ability of skeletal muscle (SM) in response to damage, injury, or disease is a highly intricate process that involves the...
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Comparative Assessment of Disturbances of Contractions of the Isolated Uterus in 3- and 9-Month-Old Rats with a Model of Autism
We performed a comparative study of the effects of carbachol, α,β-methylene-ATP, β,γ-methylene-ATP, and electric field stimulation on the contractile...
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Iatrogenic Alzheimer’s disease in recipients of cadaveric pituitary-derived growth hormone
Alzheimer’s disease (AD) is characterized pathologically by amyloid-beta (Aβ) deposition in brain parenchyma and blood vessels (as cerebral amyloid...
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Microfluidic models of the neurovascular unit: a translational view
The vasculature of the brain consists of specialized endothelial cells that form a blood-brain barrier (BBB). This barrier, in conjunction with...
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Worms of Humans
This chapter defines the group of parasitic worms, which belong to the main groups of trematodes, cestodes, nematodes, pentastomids, acanthocephalans... -
Bioartificial pulsatile cuffs fabricated from human induced pluripotent stem cell-derived cardiomyocytes using a pre-vascularization technique
There is great interest in the development of techniques to bioengineer pulsatile myocardial tissue as a next-generation regenerative therapy for...
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Histone methylation and vascular biology
The vasculature not only transports oxygenated blood, metabolites, and waste products but also serves as a conduit for hormonal communication between...
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Nickel-induced oxidative stress causes cell death in testicles: implications for male infertility
Aligarh region is well known for its lock industry. This lock industry utilises nickel for electroplating. There have been informal reports of...
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Impaired angiogenesis in ageing: the central role of the extracellular matrix
Each step in angiogenesis is regulated by the extracellular matrix (ECM). Accumulating evidence indicates that ageing-related changes in the ECM...
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Integration of Health Risk Assessment for Various Chemicals: Common Biomarkers in Different Exposure Routes
In the previous chapter, we can demonstrate rat hyperactivity through endocrine disruptors. In this chapter, it is shown that rat hyperactivity is... -
Cells and Tissues of the Immune System
This chapter, will provide a first overview on the cells and tissues forming the immune system. We will discuss the general role of immunity in... -
Distal Onco-sphere: Organotrophic Metastasis
In order for CTCs to find a suitable soil for its growth, CTCs need to assess the distal onco-sphere for suitability in terms of secreted factors,... -
Structural and Mechanical Properties of Human Superficial Femoral and Popliteal Arteries
The femoropopliteal artery (FPA) is the main artery in the lower limb. It supplies blood to the leg muscles and undergoes complex deformations during...
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Flow goes forward and cells step backward: endothelial migration
Systemic and pulmonary circulations constitute a complex organ that serves multiple important biological functions. Consequently, any pathological...
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Advances and Applications of Brain Organoids
Understanding the fundamental processes of human brain development and diseases is of great importance for our health. However, existing research...
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Vascularisation of pluripotent stem cell–derived myocardium: biomechanical insights for physiological relevance in cardiac tissue engineering
The myocardium is a diverse environment, requiring coordination between a variety of specialised cell types. Biochemical crosstalk between...
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Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances
Engineered human cardiac tissues facilitate progress in regenerative medicine, disease modelling and drug development. In this Perspective, we...
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Effects of temperature on the life cycle of Neobenedenia sp. (Monogenea: Capsalidae) from Seriola rivoliana (Almaco jack) in Bahía de La Paz, BCS Mexico
Seriola rivoliana cultivated in Mexico are infected by Neobenedenia sp. (Monogenea: Capsalidae), resulting in dermal ulceration and subsequent...
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Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review
Stroke is the third leading cause of death and long-term disability in the world. Considered largely a disease of aging, its global economic and...