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Hemoglobinopathies, merozoite surface protein-2 gene polymorphisms, and acquisition of Epstein Barr virus among infants in Western Kenya
BackgroundEpstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children...
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Colonization with multidrug-resistant Enterobacteriaceae among infants: an observational study in southern Sri Lanka
BackgroundThe timing of and risk factors for intestinal colonization with multidrug-resistant Enterobacteriaceae (MDRE) are still poorly understood...
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Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS)
IntroductionDespite being a leading infectious cause of childhood disability globally, testing for cytomegalovirus (CMV) infections in pregnancy is...
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Reduced neuronal population in the dorsolateral prefrontal cortex in infant macaques infected with simian immunodeficiency virus (SIV)
Pediatric HIV infection remains a global health crisis with an estimated 150,000 new mother-to-child (MTCT) infections each year. Antiretroviral...
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Effects of neonatal rearing by different types of foster mother on the distribution of corticotropin-releasing factor neurons in the central amygdaloid nucleus in rats
The mother–child relationship of newborns plays an essential role in the development of the central nervous system, and an inadequate relationship,...
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Interrelationship between sleep quality of 1-month old infants and their mothers’ corresponding activities
The aim was to examine the interrelationship between sleep quality of 1-month infants and mothers, mothers’ corresponding activities to infant’s...
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Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood
BackgroundAdverse childhood experiences (ACEs) increase the risk of poor health outcomes later in life. Psychosocial stressors may also have...
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DNA methylation of GFI1 as a mediator of the association between prenatal smoking exposure and ADHD symptoms at 6 years: the Hokkaido Study on Environment and Children’s Health
BackgroundPrenatal smoking exposure has been associated with childhood attention-deficit/hyperactivity disorder (ADHD). However, the mechanism...
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Prediction model for milk transfer of drugs by primarily evaluating the area under the curve using QSAR/QSPR
PurposeInformation on milk transferability of drugs is important for patients who wish to breastfeed. The purpose of this study is to develop a...
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The transition to motherhood: linking hormones, brain and behaviour
We are witnessing a stark increase in scientific interest in the neurobiological processes associated with pregnancy and maternity. Convergent...
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Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition
BackgroundThe gut microbiome undergoes primary ecological succession over the course of early life before achieving ecosystem stability around...
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Imprinted genes and the manipulation of parenting in mammals
Genomic imprinting refers to the parent-of-origin expression of genes, which originates from epigenetic events in the mammalian germ line. The...
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What Happens In Utero Does Not Stay In Utero: a Review of Evidence for Prenatal Epigenetic Programming by Per- and Polyfluoroalkyl Substances (PFAS) in Infants, Children, and Adolescents
Purpose of ReviewReview human literature on the relationship between prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and epigenetic...
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Age at first exposure to antibiotics and neurodevelopmental outcomes in childhood
RationaleViral illnesses in children are common and are frequently treated with antibiotic medication. Antibiotics reduce the diversity and...
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The association between being breastfed in infancy and risks of cancer in adulthood—a UK Biobank study
BackgroundBeing breastfed has established benefits for infant health, but its long-term effects on adult diseases, including cancer, remain...
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Recent Advances on Sleep During Pregnancy and Postpartum
Sleep differences between genders account for several biological factors impacted by a combination of environmental, social, and cultural influences.... -
Household environment and animal fecal contamination are critical modifiers of the gut microbiome and resistome in young children from rural Nicaragua
BackgroundEarly life plays a vital role in the development of the gut microbiome and subsequent health. While many factors that shape the gut...
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Maternal diabetes and risk of attention-deficit/hyperactivity disorder in offspring in a multinational cohort of 3.6 million mother–child pairs
Previous studies report an association between maternal diabetes mellitus (MDM) and attention-deficit/hyperactivity disorder (ADHD), often...
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Synbiotics for the Prevention and Treatment of Skin Disorders
A profound symbiotic relationship exists between the skin and its microbial inhabitants, integral for human survival. Perturbations in this delicate... -
Prenatal Diet as a Modifier of Environmental Risk Factors for Autism and Related Neurodevelopmental Outcomes
Purpose of ReviewEnvironmental chemicals and toxins have been associated with increased risk of impaired neurodevelopment and specific conditions...