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Palliative radiotherapy for tumor bleeding in patients with unresectable pancreatic cancer: a single-center retrospective study
BackgroundPatients with unresectable pancreatic cancer (PC) sometimes experience gastrointestinal bleeding (GIB) due to tumor invasion of the...
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Leptospira interrogans Bat proteins impair host hemostasis by fibrinogen cleavage and platelet aggregation inhibition
Leptospirosis is a worldwide spread zoonosis, caused by pathogenic Leptospira . Evidences suggest that compromised hemostasis might be involved in the...
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Effect of a New Synthetic Peptide Preparation AСTH15-18PGP on the Hemostasis System in Rats
We studied the effect of chronic intranasal and peroral administration of a new peptide preparation AСTH 15-18 PGP in a dose of 100 mg/kg body weight...
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Experimental Studies of a Thermoelectric Device to Stop Bleeding
The design of a prototype thermoelectric device (TED) for stop** bleeding by local freezing of the blood flow area is discussed. Results of field...
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A Portable Optical Device for Assessing Platelet Aggregation Activity
A portable device for point-of-care testing of native human blood has been developed. The device operation is based on digital speckle pattern...
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Measurement of Blood Viscoelasticity Using Thromboelastography
Thromboelastography (TEG) was the first viscoelastic test (VET), invented in Germany in 1948 by Dr. Hartert, and which evaluates the hemostatic... -
An overview of qualitative and quantitative platelet abnormalities in schistosomiasis
Schistosomiasis is a neglected tropical disease referring to the infection with blood parasitic trematodes of the genus Schistosoma . It impacts...
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Viscoelastic Hemostatic Assays in the Management of the Trauma Patient
Viscoelastic hemostatic assays (VHAs) have been proposed as an alternative strategy for coagulopathy monitoring, transfusion, and resuscitation... -
Viscoelastic Hemostatic Assays in the Management of the Trauma Patient
Viscoelastic hemostatic assays (VHAs) have been proposed as an alternative strategy for coagulopathy monitoring, transfusion, and resuscitation... -
Scaffold-Mediated Drug Delivery for Enhanced Wound Healing: A Review
Wound healing is a complex physiological process involving coordinated cellular and molecular events aimed at restoring tissue integrity. Acute...
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Natural agents as wound-healing promoters
AbstractThe management of acute and chronic wounds resulting from diverse injuries poses a significant challenge to clinical practices and healthcare...
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Brain-Iron Cross Talk
This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron...
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Effects of Combined Treatment with Compounds Affecting Mitochondria on Physiological Parameters in Old Monkey
Correction of mitochondrial function is a promising direction for modulating aging processes. The effect of NAD + (in the form of its precursor...
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Influence of Humoral Factors on Hemostatic Properties of Blood In Vitro in Rats
An important role in the implementation of many physiological and pathological processes is played by the functional state of the components of the...
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Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls
BackgroundMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, heterogenous disease characterized by unexplained persistent...
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3D Printing as a Technological Strategy for the Personalized Treatment of Wound Healing
Wound healing is a dynamic process which involves stages of hemostasis, inflammation, proliferation and remodeling. Any error in this process results...
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Recent advances in the discovery and development of drugs targeting the kallikrein-kinin system
BackgroundThe kallikrein-kinin system is a key regulatory cascade involved in blood pressure maintenance, hemostasis, inflammation and renal...
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Pharmacokinetic–Pharmacodynamic Modelling in Hemophilia A: Relating Thrombin and Plasmin Generation to Factor VIII Activity After Administration of a VWF/FVIII Concentrate
BackgroundHemophilia A patients are treated with factor (F) VIII prophylactically to prevent bleeding. In general, dosage and frequency are based on...
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Role of Macrophages and Immunotherapy in Wound Healing
The body undergoes four phases of healing, which are hemostasis, inflammation, proliferation, and reprogramming/remodeling, when exposed to a wound.... -
Zinc-containing Mohs’ paste affects blood flow and angiogenesis suppression
PurposeMohs’ paste, which is composed of zinc chloride and zinc oxide starch, is used for hemostasis of superficial malignancy in the clinical...