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Changes in contributions of different Anopheles vector species to malaria transmission in east and southern Africa from 2000 to 2022
BackgroundMalaria transmission in Africa is facilitated by multiple species of Anopheles mosquitoes. These vectors have different behaviors and...
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Sex differences of the shared genetic landscapes between type 2 diabetes and peripheral artery disease in East Asians and Europeans
Type 2 diabetes (T2D) is a critical risk factor for peripheral artery disease (PAD). However, the sex differences in genetic basis, causality, and...
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Presence of Cryptosporidium parvum in pre-washed vegetables from different supermarkets in South East England: A pilot study
Cryptosporidium is an important water-borne and food-borne parasite with a high burden of disease . This organism has been shown to contaminate...
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Phylogenetic position of the South American freshwater Rhipidocotyle santaensis (Digenea:Bucephalidae) based on partial 28S rDNA
The family Bucephalidae is comprised of nine subfamilies, the most important being Bucephalinae with eight genera. Among these, the genus Rhipidocotyle ...
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Inherited CARD9 Deficiency Due to a Founder Effect in East Asia
Autosomal recessive CARD9 deficiency can underly deep and superficial fungal diseases. We identified two Japanese patients, suffering from...
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Causal associations between chronic hepatitis B and COVID-19 in East Asian populations
BackgroundThe relationship between chronic hepatitis B (CHB) and Coronavirus disease 2019 (COVID-19) has been inconsistent in traditional...
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Bartonella in bat flies from the Egyptian fruit bat in the Middle East
In the family of fruit bats, Pteropodidae Gray, 1821, as in the third most diverse group of bats (Chiroptera), the bacterium of the genus Bartonella ...
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Emergence of Plasmodium falciparum strains with artemisinin partial resistance in East Africa and the Horn of Africa: is there a need to panic?
The emergence and spread of artemisinin partial resistance in East and Horn of Africa is alarming. However, artemisinin-based combination therapy...
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Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits
Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they...
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British South Asian ancestry participants views of pharmacogenomics clinical implementation and research: a thematic analysis
BackgroundSouth Asian ancestry populations are underrepresented in genomic studies and therapeutics trials. British South Asians suffer from...
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Identification and characterization of Phaseolus vulgaris endornavirus 1, 2 and 3 in common bean cultivars of East Africa
Persistent viruses include members of the family Endornavirus that cause no apparent disease and are transmitted exclusively via seed or pollen. It...
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SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort
BackgroundReported association between statin use and cataract risk is controversial. The SLCO1B1 gene encodes a transport protein responsible for...
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A Barcoding and Morphological Identification of Mosquito Species of the Genus Aedes (Diptera: Culicidae) of the Russian Far East and Northern Vietnam
AbstractWe characterized the variability of mosquitoes of the genus Aedes , subgenus Stegomyia , in the south of European Russia and in the Far East...
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Mendelian randomization analysis of 37 clinical factors and coronary artery disease in East Asian and European populations
BackgroundCoronary artery disease (CAD) remains the leading cause of mortality worldwide despite enormous efforts devoted to its prevention and...
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Community demand for comprehensive primary health care from malaria volunteers in South-East Myanmar: a qualitative study
BackgroundMalaria volunteers have contributed significantly to malaria control achieving a reduction of annual parasite incidence to pre-elimination...
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Exposure to alcohol advertising and alcohol consumption among children and early teenagers in South Africa
BackgroundThere is a paucity of information on alcohol adverts on alcohol consumption among early teenagers. The study aimed to examine the...
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Attributes of Anopheles gambiae swarms in South Central Uganda
BackgroundAnopheles gambiae continues to be widespread and an important malaria vector species complex in Uganda. New approaches to malaria vector...
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Species richness of bat flies and their associations with host bats in a subtropical East Asian region
BackgroundUnderstanding the interactions between bat flies and host bats offer us fundamental insights into the coevolutionary and ecological...
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Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries
Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with the following two subtypes: Crohn’s disease (CD) and...
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Therapeutic efficacy and safety of artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria treatment in Metehara, Central-east Ethiopia
BackgroundMalaria remains a major global health problem although there was a remarkable achievement between 2000 and 2015. Malaria drug resistance,...