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Normal Development and Pathology of Motoneurons: Anatomy, Electrophysiological Properties, Firing Patterns and Circuit Connectivity
This chapter will provide an introduction into motoneuron anatomy, electrophysiological properties, firing patternsFiring patterns focusing on...
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Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex
Primary sensory cortices respond to crossmodal stimuli—for example, auditory responses are found in primary visual cortex (V1). However, it remains...
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Dissociating the contributions of sensorimotor striatum to automatic and visually guided motor sequences
The ability to sequence movements in response to new task demands enables rich and adaptive behavior. However, such flexibility is computationally...
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Local activation of CB1 receptors by synthetic and endogenous cannabinoids dampens burst firing mode of reticular thalamic nucleus neurons in rats under ketamine anesthesia
The reticular thalamic nucleus (RTN) is a thin shell that covers the dorsal thalamus and controls the overall information flow from the thalamus to...
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Tonic serotonergic input increases the burst firing mode and diminishes the firing rate of reticular thalamic nucleus neurons through 5-HT1A receptors activation in anesthetized rats
The reticular thalamic nucleus (RTn) is a thin shell of GABAergic neurons that covers the dorsal thalamus that regulate the global activity of all...
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A sensory–motor theory of the neocortex
Recent neurophysiological and neuroanatomical studies suggest a close interaction between sensory and motor processes across the neocortex. Here, I...
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Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control
The brain generates predictive motor commands to control the spatiotemporal precision of high-velocity movements. Yet, how the brain organizes...
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Does strict validation criteria for individual motor units alter population-based regression models of the motor unit pool?
The purpose of this study was to determine if the implementation of a strict validation procedure, designed to limit the inclusion of inaccuracies...
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Flexible neural control of motor units
Voluntary movement requires communication from cortex to the spinal cord, where a dedicated pool of motor units (MUs) activates each muscle. The...
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Activity map of a cortico-cerebellar loop underlying motor planning
The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown how the two structures organize into functional networks to...
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From Parametric Representation to Dynamical System: Shifting Views of the Motor Cortex in Motor Control
In contrast to traditional representational perspectives in which the motor cortex is involved in motor control via neuronal preference for kinetics...
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Noise or signal? Spontaneous activity of dorsal horn neurons: patterns and function in health and disease
Spontaneous activity refers to the firing of action potentials by neurons in the absence of external stimulation. Initially considered an artifact or...
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The Motor of Time: Coupling Action to Temporally Predictable Events Heightens Perception
Timing and motor function share neural circuits and dynamics, which underpin their close and synergistic relationship. For instance, the temporal...
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Rhythmic firing of neurons in the medulla of conscious freely behaving rats: rhythmic coupling with baroreceptor input
Recent investigations emphasized the importance of neural control of cardiovascular adjustments in complex behaviors, including stress, exercise,...
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Neuromuscular Function: High-Density Surface Electromyography
Surface electromyography (EMG) is a noninvasive technique that has the potential to provide information on how the nervous system controls movement....
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From Physiological Properties to Selective Vulnerability of Motor Units in Amyotrophic Lateral Sclerosis
Spinal alpha-motoneurons are classified in several types depending on the contractile propertiesContractile properties of the innervated muscle...
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Reciprocal and coactivation commands at the level of individual motor units in an extrinsic finger flexor–extensor muscle pair
We explored the synergic organization of motor units in extrinsic finger muscles, flexor digitorum superficialis (FDS), and extensor digitorum...
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Comparison of decomposition algorithms for identification of single motor units in ultrafast ultrasound image sequences of low force voluntary skeletal muscle contractions
ObjectiveIn this study, the aim was to compare the performance of four spatiotemporal decomposition algorithms (stICA, stJADE, stSOBI, and sPCA) and...
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The Secondary Motor Cortex-striatum Circuit Contributes to Suppressing Inappropriate Responses in Perceptual Decision Behavior
The secondary motor cortex (M2) encodes choice-related information and plays an important role in cue-guided actions. M2 neurons innervate the dorsal...
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Genome-wide determinants of mortality and motor progression in Parkinson’s disease
There are 90 independent genome-wide significant genetic risk variants for Parkinson’s disease (PD) but currently only five nominated loci for PD...
