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Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer’s disease and experimental chronic cerebral hypoperfusion
Neurovascular unit mural cells called ‘pericytes’ maintain the blood-brain barrier and local cerebral blood flow. Pathological changes in the...
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NORHA: A NORmal Hippocampal Asymmetry Deviation Index Based on One-Class Novelty Detection and 3D Shape Features
Radiologists routinely analyze hippocampal asymmetries in magnetic resonance (MR) images as a biomarker for neurodegenerative conditions like...
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Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization
The brain forms cognitive maps of relational knowledge—an organizing principle thought to underlie our ability to generalize and make inferences....
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Artemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice
BackgroundNeuronal ferroptosis plays a critical role in the pathogenesis of cognitive deficits. The present study explored whether artemisinin...
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Analysis of Surface Expression of NMDAR Subunits in Primary Hippocampal Neurons
The expression and activity of ionotropic glutamate receptors control signal transduction at the excitatory synapses in the CNS. The NMDAR comprises...
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The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study
Rationale and objectivesThe hippocampus, especially the CA1, CA3, and dentate gyrus (DG) subfields, is reported to be associated with post-traumatic...
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Functional connectivity changes of the hippocampal subregions in anti-N-methyl-D-aspartate receptor encephalitis
The hippocampus plays an important role in the pathophysiological mechanism of Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis....
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Subclinical epileptiform discharges in Alzheimer’s disease are associated with increased hippocampal blood flow
BackgroundIn epilepsy, the ictal phase leads to cerebral hyperperfusion while hypoperfusion is present in the interictal phases. Patients with...
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RETRACTED ARTICLE: Impact of Prenatal Acetaminophen Exposure for Hippocampal Development Disorder on Mice
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesic agents. They have been detected in various environmental matrices. The...
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Predictors of hippocampal tauopathy in people with and at risk for human immunodeficiency virus infection
Combination antiretroviral therapy (cART) has extended lifespans of people living with HIV (PWH), increasing both the risk for age-related...
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Melatonin Modulates Cell Cycle Dynamics and Promotes Hippocampal Cell Proliferation After Ischemic Injury in Neonatal Rats
Promoting neural cell proliferation may represent an important strategy for enhancing brain repair after developmental brain injury. The present...
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Analysis of hippocampal local field potentials by diffusion mapped delay coordinates
Spatial navigation through novel spaces and to known goal locations recruits multiple integrated structures in the mammalian brain. Within this...
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Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer’s disease
BackgroundAdult neurogenesis occurs in the subventricular zone (SVZ) and the subgranular zone of the dentate gyrus in the hippocampus. The neuronal...
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Effect and Mechanism of LIN28 on Ferroptosis in Mg2+-free Rat Hippocampal Neuron Model of Epilepsy
Studies have demonstrated that LIN28 is expressed in the CNS and may exert protective effects on neurons. However, it remains unknown whether LIN28...
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Retinal peri-arteriolar versus peri-venular amyloidosis, hippocampal atrophy, and cognitive impairment: exploratory trial
The relationship between amyloidosis and vasculature in cognitive impairment and Alzheimer’s disease (AD) pathogenesis is increasingly acknowledged....
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The Role of Acetylation and Methylation of Rat Hippocampal Histone H3 in the Mechanism of Aluminum-Induced Neurotoxicity
Aluminum is a known neurotoxin and a major environmental contributor to neurodegenerative diseases such as Alzheimer’s disease (AD). We uesd a...
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Reaction of the Hippocampal Microglia to Hyperbaric Oxygen
We studied the reaction of rat hippocampal microgliocytes to hyperbaric oxygen at a pressure of 5 ata (absolute atmosphere). Immunohistochemical...
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Sirt1 protects against hippocampal atrophy and its induced cognitive impairment in middle-aged mice
BackgroundSirtuin 1 ( Sirt1 ) is a recognized longevity gene and has been shown to be associated with aging and its related diseases. Hippocampal...
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The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy
Targeted tissue ablation involving the anterior hippocampus is the standard of care for patients with drug-resistant mesial temporal lobe epilepsy....
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Association between salivary oxytocin levels and the amygdala and hippocampal volumes
Salivary oxytocin levels have been widely measured and studied in relation to social behavior because of procedural simplicity and noninvasiveness....
