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Molecular Cardiology
Not too long ago a textbook section entitled “Molecular Cardiology” would have seemed curiously paradoxical and impractical. Molecular biology... -
Kardiomyopathien — genetische Ursachen und Pathogenese
Als Kardiomyopathien werden Krankheiten des Herzmuskels bezeichnet, die zu einer Beeinträchtigung der systolischen und/oder diastolischen Funktion... -
A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
In an attempt to create an animal model of tissue-specif ic mitochondrial disease, we generated ‘knockout’ mice deficient in the heart/muscle isoform...
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Genetic Control of Muscle Function and Molecular Basis of Muscle Diseases
In a metazoan organism such as a worm, a fruitfly, or man, gene expression is controlled in time and space to ensure development and function of the... -
Prospects for Comparative Genome Analyses Among Mammals
The discovery of hypervariable microsatellite markers and the technical advances of marker ty** has facilitated efforts towards the construction of... -
Retroviruses and Their Roles in Chronic Inflammatory Diseases and Autoimmunity
Major advances in understanding the complex processes that regulate the immune system have been achieved. Elucidating the causes of human diseases... -
Variation in Expression of Congenital Cardiovascular Malformations within and Among Families
Congenital cardiovascular malformations (CCVM) constitute a major portion of clinically significant birth defects, with the clinical literature... -
Genetic Control of the Susceptibility to Infection with Pathogenic Bacteria
The elegant early work of Benacerraf and Germain (1978), McDevitt (1976), and others (Klein 1975; Snell et al. 1976) has clearly demonstrated the...