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Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial
There is a paucity of high-quality evidence on the effectiveness and safety of salt reduction strategies, particularly for older people, who have the...
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Physiological Salt Solutions
During pharmacological experiments on isolated tissues, in order to maintain the normal physiological conditions, artificial salt solutions are...
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Causal relationship between dietary salt intake and dementia risk: Mendelian randomization study
ObjectiveObservational research has indicated a potential link between dietary salt intake and susceptibility to dementia. However, it is important...
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Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats
The matrix glycoprotein thrombospondin-1 (THBS1) modulates nitric oxide (NO) signaling in endothelial cells. A high-salt diet induces deficiencies of...
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Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization
IntroductionThe screening of multicomponent crystal system (MCC) is a key method for improving physicochemical properties of active pharmaceutical...
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Endothelin mediates sex-differences in acclimation to high salt diet in rats
IntroductionCurrent understanding of sodium (Na + ) handling is based on studies done primarily in males. Contrary to the gradual increase in high...
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High salt diet induces cognitive impairment and is linked to the activation of IGF1R/mTOR/p70S6K signaling
A high-salt diet (HSD) has been associated with various health issues, including hypertension and cardiovascular diseases. However, recent studies...
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Linkage Map Construction and QTL Map** for Salt Tolerance in the Seedlings of Dongxiang Wild Rice (Oryza rufipogon Griff.)
AbstractSalt stress causes significant reductions in rice production worldwide; thus, improving salt tolerance is a promising approach to meet the...
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High-Salt-Diet (HSD) aggravates the progression of Inflammatory Bowel Disease (IBD) via regulating epithelial necroptosis
Due to its unclear etiology, there is no specific medicine to cure the recurrent and incurable inflammatory bowel disease (IBD). Unhealthy dietary...
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Utilization of Lipophilic Salt and Phospholipid Complex in Lipid-Based Formulations to Modulate Drug Loading and Oral Bioavailability of Pazopanib
Pazopanib hydrochloride (PAZ) displays strong intermolecular interaction in its crystal lattice structure, limiting its solubility and dissolution....
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The DOCA-Salt Model of Hypertension for Studies of Cerebrovascular Function, Stroke, and Brain Health
The brain renin-angiotensin-aldosterone system (RAAS) regulates many physiological processes including fluid and electrolyte balance, vascular...
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Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4)
The taste is biologically of intrinsic importance. It almost momentarily perceives environmental stimuli for better survival. In the early 2000s,...
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Transcriptomic Analysis Under Drought and Salt Stress Provides Insight into Genes Putatively Involved in Ginsenoside Biosynthesis in Panax japonicus Meyer
Panax japonicus Meyer, a perennial herb of the dicotyledonaceae family Araliaceae, is a rare folk traditional Chinese medicine, known as “the king of...
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Salt Environment
In order to develop physiologically relevant experiments that test electrical activity in and between neurons, it is necessary to closely model the...
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Identification of Quantitative Trait Loci Related to Salt Tolerance of Indica Rice RIL Population in Different Growth Stages
AbstractRice as one of the important crops, is limited by salt stress in different growth stages. To identify genomic regions associated with...
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Hordeum vulgare ethanolic extract mitigates high salt-induced cerebellum damage via attenuation of oxidative stress, neuroinflammation, and neurochemical alterations in hypertensive rats
High salt intake increases inflammatory and oxidative stress responses and causes an imbalance of neurotransmitters involved in the pathogenesis of...
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Heterologous expression of the TaPI-PLC1-2B gene enhanced drought and salt tolerance in transgenic rice seedlings
Drought and salt stress are important factors that affect plant growth and development and cause crop yield reductions worldwide. Phospholipase C is...
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Taking it with a grain of salt: tolerance to increasing salinization in Culex pipiens (Diptera: Culicidae) across a low-lying delta
BackgroundSalinity, exacerbated by rising sea levels, is a critical environmental cue affecting freshwater ecosystems. Predicting ecosystem structure...
