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An In Silico Modelling Approach to Predict Hemodynamic Outcomes in Diabetic and Hypertensive Kidney Disease
Early diagnosis of kidney disease remains an unmet clinical challenge, preventing timely and effective intervention. Diabetes and hypertension are...
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Targeting protein interaction networks in mitochondrial dynamics for neurodegenerative diseases
Mitochondria, the powerhouse of eukaryotic cells, are the central organelle controlling energy metabolism and apoptosis. Based on metabolic needs,...
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Unraveling metabolic pathways and key genes in Alzheimer’s, type 2 diabetes, and estrogen dysregulation among aging women: a systems biology approach
BackgroundAlzheimer’s disease (AD) and Type 2 Diabetes Mellitus (T2DM) present significant global health challenges, particularly affecting aging...
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Comparative Linkage of Novel Anti-Tumor Pd(II) Complex with Bio-Macromulecules: Fluorescence, UV-Vis, DFT, Molecular Docking and Molecular Dynamics Simulation Studies
A novel mononuclear palladium complex, [Pd(dach)(SSA)], where dach and SSA are diaminocyclohexane and sulfosalicylic acid ligands, respectively, has...
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Efficient Cardiovascular Parameters Estimation for Fluid-Structure Simulations Using Gappy Proper Orthogonal Decomposition
As full-scale detailed hemodynamic simulations of the entire vasculature are not feasible, numerical analysis should be focused on specific regions...
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Fabrication of Highly Sensitive and Selective Nitrite Colorimetric Sensor Based on the Enhanced Peroxidase Mimetic Activity of Using Acetic Acid Capped Zinc Oxide Nanosheets
Nitrite ions (NO 2 - ), as one of the leading type-A inorganic-anion, showing significant-effects in the aquatic environment and also to humans health....
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OpenHands: An Open-Source Statistical Shape Model of the Finger Bones
This paper presents statistical shape models of the four fingers of the hand, with an emphasis on anatomic analysis of the proximal and distal...
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In-Vitro Study of the Binding of Atorvastatin with Adenine using Multi-Spectroscopic Approaches
Atorvastatin—an oral lipid regulating drug is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase), which...
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Synthesis, Crystal Structure, Fluorescence and Theoretical Calculations of Three Zn(II)/Cd(II) Complexes with Bis-dentate N,N-Quinoline Schiff Base
Three d 10 metal complexes, ZnL(OAc) 2 ( 1 ), CdL(OAc) 2 ( 2 ) and [CdL 2 (NO 3 ) 2 ]·CH 3 CN ( 3 ) were synthesized using the ligand ( E )- N -(3-methoxy-4-methylphenyl)-...
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Eco-friendly Fluorescent Sensor for Sensitive and Selective Detection of Zn2+ and Fe3+ Ions: Applications in Human Hair Samples
A new eco-friendly sensor, 3-((6-((4-chlorobenzylidene)amino)pyridin-2-yl)imino)indolin-2-one ( CBAPI ) was synthesized and well characterized. The CBAPI ...
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Exploring the molecular binding mechanism of 6-fluoro, 4-hydroxy, 2- methyl quinoline with TiO2 nanoparticles: A spectroscopic, thermodynamic, and insights into the solvatochromic effect
This study investigates the interaction between titanium oxide nanoparticles (TiO 2 NPs) and the heterocyclic fluorophore...
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Investigation on the Influence of Solvents Environment on the Optoelectronic Properties of the Fluorescent Probe 1,3,4-Oxadiazole Analogues: A Combined Theoretical and Experimental Study
This study investigates the photophysical properties of a nitrobenzene-substituted 1,3,4-oxadiazole derivative (OX-NO) using both theoretical and...
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Biosynthesis, Structural, Spectroscopic, Photoluminescence, and Antifungal Activity of Ni-doped CeO2 Nanoparticles
Pedalium Murex leaf extract was used in this study to create Nickel-doped Cerium oxide (Ni-CeO 2 ) nanoparticles at 3 mol% and 5 mol% molar...
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Label-Free Monitoring of Endometrial Cancer Progression Using Multiphoton Microscopy
Endometrial cancer is the most common gynecological cancer in the developed world. However, the accuracy of current diagnostic methods is still...
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Surface Passivation of Carbon Dots for Tunable Biological Performance
Recent investigations were shifted this trend toward exploring the biomedical applicability of CDs, relevant to chronic diseases. Herein, a...
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Assessing focal spot alignment in clinical linear accelerators: a comprehensive evaluation with triplet phantoms
A fundamental parameter to evaluate the beam delivery precision and stability on a clinical linear accelerator (linac) is the focal spot position...
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The verification of the utility of a commercially available phantom combination for quality control in contrast-enhanced mammography
Contrast-enhanced mammography is being increasingly implemented clinically, providing much improved contrast between tumour and background...
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Instrumented Mouthguard Decoupling Affects Measured Head Kinematic Accuracy
Many recent studies have used boil-and-bite style instrumented mouthguards to measure head kinematics during impact in sports. Instrumented...
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Probabilistic Finite Element Analysis of Human Rib Biomechanics: A Framework for Improved Generalizability
In dynamic impact events, thoracic injuries often involve rib fractures, which are closely related to injury severity. Previous studies have...
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Dispersal of Pseudomonas aeruginosa biofilm using TDS97 bacteriophage and recombinant alginate lyase enzyme
Pseudomonas aeruginosa is an opportunistic human pathogen capable of forming biofilms and contaminate medical devices and food. Bacteremia caused by...
