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Comparative analysis of two novel complete genomes of myxoma virus vaccine strains
Myxoma virus (MYXV) is a double-stranded DNA-containing virus of the family Poxviridae , genus Leporipoxvirus . MYXV is an important model virus for...
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Molecular functions of HAX1 during disease progress
HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close...
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Five pimarane diterpenoids from Kaempferia champasakensis and their cytotoxic activities
A phytochemical investigation of Kaempferia champasakensis rhizomes led to the isolation of five new pimarane diterpenes, kaempferiols E–I ( 1–5 ). The...
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Di-caffeoylquinic acid: a potential inhibitor for amyloid-beta aggregation
Alzheimer's disease (AD) remains a challenging neurodegenerative disorder with limited therapeutic success. Traditional Chinese Medicine (TCM), as a...
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Identification of a novel monopartite begomovirus associated with leaf curl disease of Citharexylum spinosum in India
The present study reports the complete genome of a novel monopartite begomovirus, named tentatively as “Citharexylum leaf curl virus” (CitLCuV),...
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Characterization of an envelope protein 118L in invertebrate iridescent virus 6 (IIV6)
Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic insect virus and a member of the family Iridoviridae . The IIV6 genome consists of...
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Characterization of the proteins encoded by a recently emerged cotton-infecting Polerovirus
The cotton leafroll dwarf virus (CLDV), an important viral pathogen responsible for substantial losses in cotton crops, has recently emerged in the...
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Molecular epidemiology and genetic evolution of avian influenza H5N1 subtype in Nigeria, 2006 to 2021
Nigeria recorded one of the earliest outbreaks of the Highly Pathogenic Avian Influenza (HPAI) virus H5N1 in 2006, which spread to other African...
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Isolation and identification of a pigeonpox virus strain and study on the integration of reticuloendotheliosis virus sequence
In order to study the integration of reticuloendotheliosis virus (REV) in pigeonpox virus (PPV), we collected suspected pigeonpox disease material,...
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Detection of four isomers of the human cytomegalovirus genome using nanopore long-read sequencing
Human cytomegalovirus has a linear DNA genome with a total length of approximately 235 kb. This large genome is divided into two domains, "Long" and...
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Urolithin C suppresses colorectal cancer progression via the AKT/mTOR pathway
Urolithin families are gut-microbial metabolites of ellagic acid (EA). Although urolithin A (UA) and urolithin B (UB) were reported to have...
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Phylogenetic analysis and molecular genetic characteristics of West Nile virus lineage 2 isolates circulating in the Russian Federation
Since its initial detection in Africa, the West Nile virus has disseminated widely across all continents, becoming endemic in numerous countries,...
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Novel compounds isolated from health food products containing beni-koji (red yeast rice) with adverse event reports
Recently, health hazards, such as kidney damage, have been reported owing to the ingestion of a health food product, so-called “foods with functional...
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The potential emerging role of piRNA/PIWI complex in virus infection
P-element-induced wimpy testis-interacting RNAs (piRNAs), a class of small noncoding RNAs with about 24–32 nucleotides, often interact with PIWI...
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White yam (Dioscorea rotundata) plants exhibiting virus-like symptoms are co-infected with a new potyvirus and a new crinivirus in Ethiopia
White yam ( Dioscorea rotundata ) plants collected from farmers’ fields and planted at the Areka Agricultural Research Center, Southern Ethiopia,...
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The full genome characterization of avian encephalomyelitis virus, Iran: a vertical transmission case
Avian encephalomyelitis (AE) is an important infectious poultry disease worldwide that is caused by avian encephalomyelitis virus (AEV). The...
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Byakangelicin alleviates sepsis-associated acute kidney injury by inhibiting inflammation and apoptosis
Inflammation and apoptosis are common in many pathological conditions. Studies have shown that many natural compounds can regulate the signal...
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Germacrone, isolated from Curcuma wenyu**, inhibits melanin synthesis through the regulation of the MAPK signaling pathway
Abnormal melanin synthesis causes hyperpigmentation disorders, such as chloasma, freckles, and melanoma, which are highly multiple and prevalent....
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Scutellaria Root extract-induced hepatocytotoxicity can be controlled by regulating its baicalin content
Scuellaria Root ( SR , root of Scutellaria baicalensis ), which has potent anti-inflammatory effects, is a component of useful Kampo formulae. Albeit a...
