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Article
Open AccessNuclear alpha-synuclein accelerates cell senescence and neurodegeneration
The progression of Parkinson’s disease (PD) is related to ageing. The accumulation of nuclear alpha-synuclein (α-syn) may accelerate the occurrence of neurodegenerative diseases, but its role in PD remains poo...
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Article
Open AccessGenetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...
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Article
Asymmetric catalytic synthesis of chiral covalent organic framework composite (S)-DTP-COF@SiO2 for HPLC enantioseparations by normal-phase and reversed-phase chromatographic modes
A novel CCOF core–shell composite material (S)-DTP-COF@SiO2 was prepared via asymmetric catalytic and in situ growth strategy. The prepared (S)-DTP-COF@SiO2 was utilized as separation medium for HPLC enantiosepar...
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Article
Bispecific BCMA/CD19 targeted CAR-T cell therapy forces sustained disappearance of symptoms and anti-acetylcholine receptor antibodies in refractory myasthenia gravis: a case report
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Article
Mining Pressure Distribution Law and Disaster Prevention of Isolated Island Working Face Under the Condition of Hard “Umbrella Arch”
Aiming at the problem of safe mining of coal seam under the condition of hard roof, taking **agou coal mine as the background, the expression of coal seam supporting force in isolated island working face minin...
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Article
Open AccessNovel inflammatory and insulin resistance indices provide a clue in cerebral amyloid angiopathy
This study investigated the correlation of newly identified inflammatory and insulin resistance indices with cerebral amyloid angiopathy (CAA), and explored their potential to differentiate CAA from hypertensi...
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Article
Karst fissures mitigate the negative effects of drought on plant growth and photosynthetic physiology
Hard limestone substrates, which are extensively distributed, are believed to exacerbate drought and increase the difficulty of restoration in vulnerable karst regions. Fissures in such substrates may alleviat...
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Article
Open AccessFerroptosis-related lncRNA NRAV affects the prognosis of hepatocellular carcinoma via the miR-375-3P/SLC7A11 axis
Ferroptosis has important value in cancer treatment. It is significant to explore the new ferroptosis-related lncRNAs prediction model in Hepatocellular carcinoma (HCC) and the potential molecular mechanism of...
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Article
Open AccessConstraints on Einstein-dilaton Gauss-Bonnet gravity with Taiji
In the 2030s, space-based gravitational-wave (GW) detectors will exhibit unprecedented sensitivity in the millihertz frequency band, greatly expanding the potential for testing theories of gravity compared to ...
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Article
Magnetic Shield Design and Simulation Optimization of Metallic Magnetic Calorimeter in Ultra-Low Temperature Working State
Metallic magnetic calorimeters (MMC) are low-temperature particle detectors based on calorimetry. They typically operate at temperatures below 100 mK. They utilize a metallic paramagnetic temperature sensor to...
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Article
Open AccessAge-, sex- and proximal–distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates
The incidence of intestinal diseases increases with age, yet the mechanisms governing gut aging and its link to diseases, such as colorectal cancer (CRC), remain elusive. In this study, while considering age, ...
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Article
Effect of Vacuum Degrees on Interfacial Bonding Behavior of 7050 Aluminum Alloy Clad Plates During Hot-Roll Cladding
Interfacial bonding behavior of 7050 aluminum alloy clad plates during hot-roll cladding under different vacuum degrees was investigated. The results demonstrated that the bonding effect of the interface was p...
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Article
Open AccessThe comparison of corneal higher-order aberration and surgically induced astigmatism between the clear corneal incision and the limbus tunnel incision of posterior chamber implantable collamer lens implantation
This study aimed to compare the corneal high-order aberrations and surgically induced astigmatism between the clear corneal incision and limbus tunnel incision for posterior chamber implantable collamer lens (...
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Article
Open AccessSolvent effects on terpenoid compositions and antioxidant activities of Cinnamomum camphora (L.) J. Presl extracts and the main antioxidant agent evaluation through in vitro and in vivo assay
Plant secondary metabolites can protect organisms against oxidative stress caused by adverse environmental conditions. Cinnamomum camphora (L.) J. Presl contains plentiful terpenoids and is subdivided into 5 chem...
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Chapter and Conference Paper
Effect of Schroth Exercise on Pulmonary Function and Exercise Capacity in Patients with Severe Adolescent Idiopathic Scoliosis
Purpose: This study aimed to investigate the effect of Schroth exercise on pulmonary function and exercise capacity in patients with severe adolescent idiopathic scoliosis (AIS). Methods: Forty subjects with seve...
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Chapter and Conference Paper
Research on Innovative Social Service Training Mode in Higher Vocational Colleges Under the New Situation
In the new era, vocational colleges are devoted to internal development and high-quality growth, exploring innovative models of social service training. This is an effective measure to enhance the social recog...
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Chapter and Conference Paper
Pilot Study on Enhanced Oil Recovery by Gravity Assisted Deoxygenated Air Flooding in N Fault Block
In order to solve the problem of poor water flooding development effect of extra-low permeability reservoir in Dagang Oilfield, N fault block is selected to carry out continuous gas injection and intermittent ...
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Article
Open AccessAssociations between spinal flexibility and bracing outcomes in adolescent idiopathic scoliosis: a literature review
To identify the existing assessment methods used to measure the spinal flexibility of adolescents with idiopathic scoliosis before bracing and to evaluate the predictive effect of spinal flexibility on bracing...
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Article
Burden Effects on Rock Fragmentation and Damage, and Stress Wave Attenuation in Cut Blasting of Large-Diameter Long-Hole Stopes
Cut blasting with single free surface is the first step of the large-diameter long-hole (LDL) mining method, which creates more relief space for subsequent blasting procedures. The minimum burden (W) is a critica...
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Article
Pure laparoscopic versus open left lateral hepatectomy in pediatric living donor liver transplantation: a review and meta-analysis
The meta-analysis was conducted to evaluate the safety and feasibility of pure laparoscopic left lateral hepatectomy in comparison with open approach for pediatric living donor liver transplantation (LDLT).
