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Article
Factors affecting antimonate bioreduction by Dechloromonas sp. AR-2 and Propionivibrio sp. AR-3
The microbial reduction of antimonate (Sb(v)) to antimonite (Sb(iii)), which forms insoluble Sb compounds, is a promising approach to remove antimony (Sb) from wastewater. Among the bacterial strains capable of r...
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Article
Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis
Hyperactivation of EGFR/PI3K/AKT is a prominent feature of various human cancers. Thus, understanding how this molecular cascade is balanced is of great importance. We report here that the ubiquitin-specific p...
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Article
Open AccessJMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component
Melanoma, originated from melanocytes located on the basal membrane of the epithelial tissue, is the most aggressive form of skin cancer that accounts for 75% of skin cancer-related death. Although it is belie...
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Article
Open AccessZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin
EGFR is required for animal development, and dysregulation of EGFR is critically implicated in malignant transformation. However, the molecular mechanism underlying the regulation of EGFR expression remains po...