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  1. No Access

    Article

    Synthesis of fluorinated CaCO3-based oxygen-supplying nanophotosensitizers to potentiate photodynamic immunotherapy by reversing tumor hypoxia and immunosuppression

    Photodynamic therapy is a noninvasive type of phototherapy with a high capacity to boost specific antitumor immunity by causing immunogenic cell death. However, the photodynamic therapeutic potency toward soli...

    Yunyun Zhang, Ziliang Dong, Yu Hao, Yimou Gong, Chunjie Wang, Yifan Yan in Nano Research (2023)

  2. Article

    A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy

    Cancer metastases and recurrence after surgical resection remain an important cause of treatment failure. Here we demonstrate a general strategy to fabricate personalized nanovaccines based on a cationic fluor...

    Jun Xu, Jia Lv, Qi Zhuang, Zong** Yang, Zhiqin Cao, Ligeng Xu in Nature Nanotechnology (2020)

  3. No Access

    Article

    Metal-polyphenol-network coated CaCO3 as pH-responsive nanocarriers to enable effective intratumoral penetration and reversal of multidrug resistance for augmented cancer treatments

    Construction of multifunctional stimuli-responsive nanotherapeutics enabling improved intratumoral penetration of therapeutics and reversal of multiple-drug resistance (MDR) is potent to achieve effective canc...

    Ziliang Dong, Yu Hao, Quguang Li, Zhijuan Yang, Yujie Zhu, Zhuang Liu in Nano Research (2020)

  4. No Access

    Article

    The enhanced permeability and retention effect based nanomedicine at the site of injury

    The enhanced permeability retention (EPR) effect based nanomedicine has been widely used for tumor targeting during the past decades. Here we unexpectedly observed the similar “EPR effect” at the site of injur...

    Yingjun Liu, Dongdong Sun, Qin Fan, Qingle Ma, Ziliang Dong, Weiwei Tao in Nano Research (2020)

  5. No Access

    Article

    Two-dimensional metal-organic-framework as a unique theranostic nano-platform for nuclear imaging and chemo-photodynamic cancer therapy

    Nanoscale metal organic frameworks (NMOFs) with porous structure and inherent biodegradability are attractive nanomedicine platforms. In addition to conventional particulate NMOFs, two-dimensional (2D) NMOFs a...

    Wenjun Zhu, Yu Yang, Qiutong **, Yu Chao, Longlong Tian, **g**g Liu in Nano Research (2019)

  6. No Access

    Article

    NIR-II light activated photodynamic therapy with protein-capped gold nanoclusters

    The use of near-infrared (NIR) light for photodynamic therapy (PDT) is a promising strategy to circumvent the limitations of current PDT, in which visible light with limited tissue penetration depth is usually...

    Qian Chen, Jiawen Chen, Zhijuan Yang, Lin Zhang, Ziliang Dong, Zhuang Liu in Nano Research (2018)

  7. No Access

    Article

    Nanoscale covalent organic polymers as a biodegradable nanomedicine for chemotherapy-enhanced photodynamic therapy of cancer

    Recently, covalent-organic polymers (COPs), which covalently cross-link different types of organic molecules to form organic network structures, have received significant attention in various fields. However, ...

    Hairong Wang, Wenwen Zhu, Liangzhu Feng, Qian Chen, Yu Chao, Ziliang Dong in Nano Research (2018)

  8. Article

    Open Access

    Core-shell and co-doped nanoscale metal-organic particles (NMOPs) obtained via post-synthesis cation exchange for multimodal imaging and synergistic thermo-radiotherapy

    Nanoscale metal-organic particles (NMOPs) have recently shown great promise in the area of nanomedicine owing to their tunable compositions, highly enriched functionalities, well-defined sizes/shapes and intri...

    Yu Yang, Yu Chao, **g**g Liu, Ziliang Dong, Weiwei He, Rui Zhang in NPG Asia Materials (2017)