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  1. No Access

    Article

    Autophagy Balances Neuroinflammation in Alzheimer’s Disease

    Autophagy is a highly evolutionary conserved process that degrades cytosolic macromolecules or damaged organelles (e.g., mitochondria), as well as intracellular pathogens for energy and survival. Dysfunction o...

    Xuehua Cheng, Yong Wei, Zijun Qian, Li Han in Cellular and Molecular Neurobiology (2023)

  2. No Access

    Article

    The biological functions and clinical applications of exosomes in lung cancer

    Lung cancer remains the leading cause of cancer-related death worldwide, and the high incidence rates are worrisome. Exosomes are a class of extracellular vesicles secreted by most cells, including RNAs, prote...

    Rui Chen, **n Xu, Zijun Qian, Congcong Zhang… in Cellular and Molecular Life Sciences (2019)

  3. Article

    Open Access

    Exosomes in hepatocellular carcinoma: a new horizon

    Exosomes are a class of extracellular vesicles released by multiple cells types including tumor cells, with a size range of 30-100 nm and a lipid bilayer membrane. Recently, the role of exosomes in cell-to-cel...

    Rui Chen, **n Xu, Yuquan Tao, Zijun Qian, Yongchun Yu in Cell Communication and Signaling (2019)

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  4. Article

    Open Access

    circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma

    Some types of circular RNA (circRNA) are aberrantly expressed in human diseases including hepatocellular carcinoma (HCC). However, its regulation mechanism and diagnostic roles are largely unknown. Here, we id...

    **ao Zhang, Yanfeng Xu, Zijun Qian, Weisheng Zheng, Qi Wu, Yan Chen… in Cell Death & Disease (2018)

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  5. No Access

    Article

    Efficient in situ separation and production of l-lactic acid by Bacillus coagulans using weak basic anion-exchange resin

    To get rid of the dependence on lactic acid neutralizer, a simple and economical approach for efficient in situ separation and production of l-lactic acid was established by Bacillus coagulans using weak basic an...

    Yitong Zhang, Zijun Qian, Peng Liu, Lei Liu… in Bioprocess and Biosystems Engineering (2018)