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  1. No Access

    Article

    Inferences for extended partially linear single-index models

    In partially linear single-index models, there are two different covariate matrices in the model for the linear part and nonlinear part. All covariate information needs to be divided into two parts before the ...

    Zijuan Chen, Suo** Wang in TEST (2023)

  2. Article

    Open Access

    β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion

    Virus infection may induce excessive interferon (IFN) responses that can lead to host tissue injury or even death. β-arrestin 2 regulates multiple cellular events through the G protein-coupled receptor (GPCR) ...

    Yihua Zhang, Manman Li, Liuyan Li, Gui Qian, Yu Wang, Zijuan Chen… in Nature Communications (2020)

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  3. Article

    Open Access

    PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1

    Excessive or uncontrolled release of proinflammatory cytokines caused by severe viral infections often results in host tissue injury or even death. Phospholipase C (PLC)s degrade phosphatidylinositol-4, 5-bisp...

    Lin Wang, Yilong Zhou, Zijuan Chen, Lei Sun, Juehui Wu, Haohao Li… in Nature Communications (2019)

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  4. No Access

    Article

    Modulation of host signaling in the inflammatory response by enteropathogenic Escherichia coli virulence proteins

    To successfully infect host cells and evade the host immune response, a type III secretion system (T3SS) is commonly used by enteric bacterial pathogens such as enteropathogenic Escherichia coli (EPEC). Recent fi...

    **aonan Zhuang, Zijuan Chen, Chenxi He, Lin Wang… in Cellular & Molecular Immunology (2017)

  5. No Access

    Chapter

    Posttranslational Modification Control of Inflammatory Signaling

    Inflammation is usually the defensive reaction of the immune system to the invasion of pathogen and the exogenous objects. The activation of inflammation helps our body to eliminate pathogenic microbe, virus, ...

    Yibo Si, Yunlu Zhang, Zijuan Chen… in Regulation of Inflammatory Signaling in He… (2017)

  6. No Access

    Article

    Proteomic insights into the temperature responses of a cold-adaptive archaeon Methanolobus psychrophilus R15

    Cold-adaptive methanogens contribute significantly to methane emission from the cold area, while the cold-adaptive mechanisms used by Archaea remain elusive. Methanolobus psychrophilus R15, a cold-adaptive methan...

    Zijuan Chen, Deqin Feng, Bo Zhang, Qian Wang, Yuanming Luo, **uzhu Dong in Extremophiles (2015)

  7. Article

    Open Access

    Psychrotolerant methanogenic archaea: Diversity and cold adaptation mechanisms

    Because of their diversity and abundance in a wide range of environments, particularly in cold regions, cold-adaptive archaea are expected to play a pivotal role in material recycling in cold environments. Met...

    **uZhu Dong, ZiJuan Chen in Science China Life Sciences (2012)

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