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Article
Influence of build orientation and support structure on additive manufacturing of human knee replacements: a computational study
Develo** patient-specific implants has an increasing interest in the application of emerging additive manufacturing (AM) technologies. On the other hand, despite advances in total knee replacement (TKR), stu...
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Article
Open AccessThe role of the immune system in early-onset schizophrenia: identifying immune characteristic genes and cells from peripheral blood
Early-onset schizophrenia (EOS) is a type of schizophrenia (SCZ) with an age of onset of < 18 years. An abnormal inflammatory immune system may be involved in the occurrence and development of SCZ. We aimed to...
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Article
Open AccessThe relationship between symptomatic status and aneurysm wall enhancement characteristics of single unruptured intracranial aneurysm
We aimed to analyze the aneurysm wall enhancement (AWE) characteristics of a single unruptured intracranial aneurysm (UIA) and observe the relationship between the symptoms of a single UIA and the aneurysm wall.
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Article
Open AccessNon-IG::MYC in diffuse large B-cell lymphoma confers variable genomic configurations and MYC transactivation potential
MYC translocation occurs in 8–14% of diffuse large B-cell lymphoma (DLBCL), and may concur with BCL2 and/or BCL6 translocation, known as double-hit (DH) or triple-hit (TH). DLBCL-MYC/BCL2-DH/TH are largely germin...
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Article
Study on Stress – Fluid Coupling of Coal Seam Floor Water Outburst Based on FLAC 3D Simulation
Coal mine water outburst under fluid-solid coupling is a hot topic in coal geology. In this paper, the FLAC 3D simulation method is used to systematically study the water outburst problem of fluid coupling wit...
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Article
Open AccessFully Dynamic Contraction Hierarchies with Label Restrictions on Road Networks
In the real world, road networks with weight and label on edges can be applied in several application domains. The shortest path query with label restrictions has been receiving increasing attention recently. ...
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Article
Stacked rigid and compliant dielectric structures for increasing force range in soft capacitive sensors
Soft force sensors have many applications in robotics and industrial environments. One challenge is obtaining a wide force range from common compliant materials. The capacitive sensor presented expands the ran...
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Article
Open AccessA novel defined pyroptosis-related gene signature predicts prognosis and correlates with the tumour immune microenvironment in lung adenocarcinoma
Lung adenocarcinoma (LUAD) is one of the most common causes of cancer-related death. The role of pyroptosis in LUAD remains unclear. Our study aimed to identify a prognostic signature of pyroptosis-related gen...
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Article
Open AccessCorrection: Tuberculosis in older adults: case studies from four countries with rapidly ageing populations in the western pacific region
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Article
A region-scale decoupling effort analysis of carbon dioxide emissions from the perspective of electric power industry: a case study of China
The goal of carbon peak and carbon neutralization puts forward higher requirements for the energy and electricity industry development in China. **g-**-ji region (short for Bei**g, Tian** and Hebei Provinc...
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Article
Open AccessCorrection: Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells
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Article
Open AccessTuberculosis in older adults: case studies from four countries with rapidly ageing populations in the western pacific region
The Western Pacific Region has one of the fastest-growing populations of older adults (≥ 65 years) globally, among whom tuberculosis (TB) poses a particular concern. This study reports country case studies fro...
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Article
Open AccessCorrection: Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial
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Article
Coupled folding-upon-binding of human tumor suppressor MIG6 to lung cancer EGFR kinase domain and molecular trimming/stapling of MIG6-derived β-hairpins to target the coupling event
Human epidermal growth factor receptor (EGFR) is involved in strong association with malignant proliferation, which has been shown to play a central role in the development and progression of non-small cell lu...
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Chapter and Conference Paper
Edge Coloring on Dynamic Graphs
Graph edge coloring is a fundamental problem in graph theory and has been widely used in a variety of applications. Existing solutions for edge coloring mainly focus on static graphs. However, many graphs in r...
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Chapter and Conference Paper
Contraction Hierarchies with Label Restrictions Maintenance in Dynamic Road Networks
In the real world, road networks with weight and label on edges can be applied in several application domains. The shortest path query with label restrictions has been receiving increasing attention recently. ...
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Article
Open AccessNoninvasive prenatal diagnosis targeting fetal nucleated red blood cells
Noninvasive prenatal diagnosis (NIPD) aims to detect fetal-related genetic disorders before birth by detecting markers in the peripheral blood of pregnant women, holding the potential in reducing the risk of f...
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Article
Open AccessCorrection: Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial
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Article
Open AccessOlverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial
BCR-ABL1T315I mutations confer resistance to tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia (CML). Olverembatinib is a new potent BCR-ABL1 TKI with preclinical activity against T315I-mutated CML. I...
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Article
Open AccessThyroid MALT lymphoma: self-harm to gain potential T-cell help
The development of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is driven by chronic inflammatory responses and acquired genetic changes. To investigate its genetic bases, we p...
