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Divergent age-associated and metabolism-associated gut microbiome signatures modulate cardiovascular disease risk

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  1. Article

    Open Access

    Metagenomic analysis reveals crosstalk between gut microbiota and glucose-lowering drugs targeting the gastrointestinal tract in Chinese patients with type 2 diabetes: a 6 month, two-arm randomised trial

    The use of oral glucose-lowering drugs, particularly those designed to target the gut ecosystem, is often observed in association with altered gut microbial composition or functional capacity in individuals wi...

    **uying Zhang, Huahui Ren, Cuiling Zhao, Zhun Shi, Li Qiu, Fangming Yang in Diabetologia (2022)

  2. Article

    Open Access

    Characterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic of Coronavirus disease 2019 (COVID-19). However, the microbial composition of the respiratory tract and other infected ...

    Huanzi Zhong, Yanqun Wang, Zhun Shi, Lu Zhang, Huahui Ren, Weiqun He in Cell Discovery (2021)

  3. Article

    Open Access

    Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)

    Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeo...

    Yifei Zhang, Yanyun Gu, Huahui Ren, Shujie Wang, Huanzi Zhong in Nature Communications (2020)

  4. Article

    Open Access

    Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children

    The gut microbiota evolves from birth and is in early life influenced by events such as birth mode, type of infant feeding, and maternal and infant antibiotics use. However, we still have a gap in our understa...

    Huanzi Zhong, John Penders, Zhun Shi, Huahui Ren, Kaiye Cai, Chao Fang in Microbiome (2019)