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Article
Divergent age-associated and metabolism-associated gut microbiome signatures modulate cardiovascular disease risk
Insight into associations between the gut microbiome with metabolism and aging is crucial for tailoring interventions to promote healthy longevity. In a discovery cohort of 10,207 individuals aged 40–93 years,...
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Article
Open AccessMetagenomic analysis reveals crosstalk between gut microbiota and glucose-lowering drugs targeting the gastrointestinal tract in Chinese patients with type 2 diabetes: a 6 month, two-arm randomised trial
The use of oral glucose-lowering drugs, particularly those designed to target the gut ecosystem, is often observed in association with altered gut microbial composition or functional capacity in individuals wi...
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Article
Open AccessCharacterization of respiratory microbial dysbiosis in hospitalized COVID-19 patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic of Coronavirus disease 2019 (COVID-19). However, the microbial composition of the respiratory tract and other infected ...
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Article
Sex- and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities
Lifelong sex- and age-related trajectories of the human gut microbiota remain largely unexplored. Using metagenomics, we derived the gut microbial composition of 2,338 adults (26–76 years) from a Han Chinese p...
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Article
Open AccessGut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeo...
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Article
Construction of n-TiO2/p-Ag2O Junction on Carbon Fiber Cloth with Vis–NIR Photoresponse as a Filter-Membrane-Shaped Photocatalyst
The development of effective and reusable photocatalysts with broad-spectra activity has attracted attention. Herein, we have constructed n-TiO2/p-Ag2O junction on carbon fiber (CF) cloth as an efficient and recy...
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Article
Open AccessImpact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children
The gut microbiota evolves from birth and is in early life influenced by events such as birth mode, type of infant feeding, and maternal and infant antibiotics use. However, we still have a gap in our understa...