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  1. No Access

    Article

    S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer

    The development of resistance to EGFR Tyrosine kinase inhibitors (TKIs) in NSCLC with activating EGFR mutations is a critical limitation of this therapy. In addition to genetic alterations such as EGFR seconda...

    Hua Shen, Gao-Chan Wang, **ang Li, **n Ge, Meng Wang, Zhu-Mei Shi… in Oncogene (2020)

  2. Article

    Open Access

    Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer

    Estrogen plays a critical role in breast cancer (BC) progression through estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the malignant progress of BC cells is influenced by the c...

    Cheng-Fei Jiang, Zhu-Mei Shi, Dong-Mei Li, Ying-Chen Qian, Yi Ren… in Molecular Cancer (2018)

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  3. No Access

    Article

    MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2

    Recently, several microRNAs (miRNAs) were reported to be involved in the modulation of glioma development. The aim of our study was to determine the effect of miR-181d on the growth of glioma and to investigat...

    **e-Feng Wang, Zhu-Mei Shi, **-Rui Wang… in Journal of Cancer Research and Clinical On… (2012)