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Dynamic diffusion imaging changes and unique midbrain involvement in a probable MV2K sCJD

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  1. Article

    Open Access

    Clinical features of COVID-19-related encephalitis: comparison with the features of herpes virus encephalitis and autoimmune encephalitis

    Identifying coronavirus disease 2019 (COVID-19)-related encephalitis without clear etiological evidence is clinically challenging. The distinctions between this condition and other prevalent encephalitis types...

    Yue Cui, Zhongyun Chen, Yu Kong, Yingtao Wang, Yihao Wang in Neurological Sciences (2024)

  2. Article

    Open Access

    Application of the mild behavioral impairment checklist in Chinese patients with the behavioral variant of frontotemporal dementia

    The mild behavioral impairment checklist (MBI-C) designed to capture neuropsychiatric symptoms in the whole spectrum of elder with or without dementia, have been verified in mild behavioral impairment, mild co...

    Yue Cui, Li Liu, Min Chu, Kexin **e, Zhongyun Chen, Haitian Nan in Neurological Sciences (2024)

  3. Article

    Open Access

    Presence of anti-IgLON5 antibody in a case of sporadic Creutzfeldt–Jakob disease with sleep disturbance as a prominent symptom

    Zhongyun Chen, **g Zhang, Yu Kong, Haitian Nan, Li Liu, Lin Wang in Neurological Sciences (2023)

  4. Article

    Open Access

    Neutrophil to High-density Lipoprotein ratio (NHR) as a potential predictor of disease severity and survival time in Creutzfeldt-Jakob disease

    Creutzfeldt-Jakob disease (CJD) is a fatal and irreversible neurodegenerative disease. Identification of inexpensive and easy-to-implement biomarkers of CJD which could predict disease severity and patient sur...

    Yu Kong, Zhongyun Chen, **g Zhang, Liyong Wu in BMC Neurology (2023)

  5. Article

    Open Access

    Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia

    Behavioral variant frontotemporal dementia (bvFTD) is predominantly considered a dysfunction in cortico-cortical transmission, with limited direct investigation of cortical-subcortical transmission. Thus, we a...

    Li Liu, Min Chu, Binbin Nie, Deming Jiang, Kexin **e in Alzheimer's Research & Therapy (2023)

  6. Article

    Open Access

    A longitudinal 18F-FDG PET/MRI study in asymptomatic stage of genetic Creutzfeldt–Jakob disease linked to G114V mutation

    Pathogenic prion protein may start to deposit in some brain regions and cause functional alterations in the asymptomatic stage in Creutzfeldt–Jakob disease. The study aims to determine the trajectory of the br...

    Min Chu, Zhongyun Chen, Binbin Nie, Li Liu, Kexin **e, Yue Cui in Journal of Neurology (2022)

  7. Article

    Open Access

    Proposal of new diagnostic criteria for fatal familial insomnia

    The understanding of fatal familial insomnia (FFI), a rare neurodegenerative autosomal dominant prion disease, has improved in recent years as more cases were reported. This work aimed to propose new diagnosti...

    Min Chu, Kexin **e, **g Zhang, Zhongyun Chen, Imad Ghorayeb in Journal of Neurology (2022)

  8. Article

    Open Access

    Genetic prion diseases presenting as frontotemporal dementia: clinical features and diagnostic challenge

    To elucidate the clinical and ancillary features of genetic prion diseases (gPrDs) presenting with frontotemporal dementia (FTD) to aid early identification.

    Zhongyun Chen, Min Chu, Li Liu, **g Zhang, Yu Kong in Alzheimer's Research & Therapy (2022)

  9. Article

    Open Access

    Adaptive optical microscopy via virtual-imaging-assisted wavefront sensing for high-resolution tissue imaging

    Adaptive optics (AO) is a powerful tool for optical microscopy to counteract the effects of optical aberrations and improve the imaging performance in biological tissues. The diversity of sample characteristic...

    Zhou Zhou, Jiangfeng Huang, **ang Li, **ujuan Gao, Zhongyun Chen, Zhenfei Jiao in PhotoniX (2022)

  10. Article

    Open Access

    Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

    Studies exploring topological properties of the metabolic network during the presymptomatic stage of genetic frontotemporal dementia (FTD) are scarce. However, such knowledge is important for understanding bra...

    Li Liu, Min Chu, Binbin Nie, Lin Liu, Kexin **e, Yue Cui in Alzheimer's Research & Therapy (2022)

  11. Article

    Open Access

    Cerebrospinal fluid Aβ42, t-tau, and p-tau levels in the differential diagnosis of idiopathic normal-pressure hydrocephalus: a systematic review and meta-analysis

    The purpose of this systematic review and meta-analysis was to evaluate the performance of cerebrospinal fluid (CSF) beta amyloid 42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) as potential diagn...

    Zhongyun Chen, Chunyan Liu, Jie Zhang, Norman Relkin in Fluids and Barriers of the CNS (2017)