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  1. Article

    Open Access

    Cerebrospinal fluid Aβ42, t-tau, and p-tau levels in the differential diagnosis of idiopathic normal-pressure hydrocephalus: a systematic review and meta-analysis

    The purpose of this systematic review and meta-analysis was to evaluate the performance of cerebrospinal fluid (CSF) beta amyloid 42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) as potential diagn...

    Zhongyun Chen, Chunyan Liu, Jie Zhang, Norman Relkin… in Fluids and Barriers of the CNS (2017)

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  2. Article

    Open Access

    MRI assessment of the effects of acetazolamide and external lumbar drainage in idiopathic Normal Pressure Hydrocephalus

    The objective was to identify changes in quantitative MRI measures in patients with idiopathic normal pressure hydrocephalus (iNPH) occurring in common after oral acetazolamide (ACZ) and external lumbar draina...

    Milos Ivkovic, Martin Reiss-Zimmermann, Heather Katzen… in Fluids and Barriers of the CNS (2015)

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  3. No Access

    Article

    Clinical Trials of Intravenous Immunoglobulin for Alzheimer’s Disease

    The human polyclonal IgG antibody preparation known as Intravenous Immunoglobulin (IVIG) has been under study as a potential treatment for Alzheimer’s disease (AD) since 2002. Preclinical and clinical studies ...

    Norman Relkin in Journal of Clinical Immunology (2014)

  4. No Access

    Article

    Human Cerebrospinal Fluid Apolipoprotein E Isoforms are Apparently Inefficient at Complexing with Synthetic Alzheimer’s Amyloid-β Peptide (Aß1−40) in vitro

    Variation at the apolipoprotein E locus on chromosome 19 plays a role in more cases of Alzheimer’s disease than does any other identified genetic determinant. We have previously reported the isoform-specific i...

    Zhongmin Zhou, Norman Relkin, Jorge Ghiso, Jonathan D. Smith… in Molecular Medicine (2002)