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  1. Article

    Open Access

    Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia

    Behavioral variant frontotemporal dementia (bvFTD) is predominantly considered a dysfunction in cortico-cortical transmission, with limited direct investigation of cortical-subcortical transmission. Thus, we a...

    Li Liu, Min Chu, Binbin Nie, Deming Jiang, Kexin **e in Alzheimer's Research & Therapy (2023)

  2. Article

    Open Access

    Genetic prion diseases presenting as frontotemporal dementia: clinical features and diagnostic challenge

    To elucidate the clinical and ancillary features of genetic prion diseases (gPrDs) presenting with frontotemporal dementia (FTD) to aid early identification.

    Zhongyun Chen, Min Chu, Li Liu, **g Zhang, Yu Kong in Alzheimer's Research & Therapy (2022)

  3. Article

    Open Access

    Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

    Studies exploring topological properties of the metabolic network during the presymptomatic stage of genetic frontotemporal dementia (FTD) are scarce. However, such knowledge is important for understanding bra...

    Li Liu, Min Chu, Binbin Nie, Lin Liu, Kexin **e, Yue Cui in Alzheimer's Research & Therapy (2022)

  4. No Access

    Article

    Lower uric acid level may be associated with hemorrhagic transformation but not functional outcomes in patients with anterior circulation acute ischemic stroke undergoing endovascular thrombectomy

    To determine the correlation of uric acid (UA) with hemorrhagic transformation (HT) and poor short-term functional outcomes in anterior circulation acute ischemic stroke (AIS) patients after endovascular throm...

    Zhongyun Chen, Hongbo Chen, Yingbo Zhang, Yanbo He, Yingying Su in Metabolic Brain Disease (2020)

  5. Article

    Open Access

    Cerebrospinal fluid Aβ42, t-tau, and p-tau levels in the differential diagnosis of idiopathic normal-pressure hydrocephalus: a systematic review and meta-analysis

    The purpose of this systematic review and meta-analysis was to evaluate the performance of cerebrospinal fluid (CSF) beta amyloid 42 (Aβ42), total tau (t-tau), and phosphorylated tau (p-tau) as potential diagn...

    Zhongyun Chen, Chunyan Liu, Jie Zhang, Norman Relkin in Fluids and Barriers of the CNS (2017)