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Open AccessIn vivo skin penetration and metabolic path of quantum dots
The skin is the largest organ of the body and is a potential route of exposure to sunscreens and cosmetics containing nanoparticles; however, the permeability of the skin to these nanoparticles is currently un...
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Article
Open AccessRapid development of proteomics in China: from the perspective of the Human Liver Proteome Project and technology development
Proteomics focuses on the systematic identification and quantification of entire proteomes and interpretation of proteins’ biological functions. During the last decade, proteomics in China has grown much faste...
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Article
Open AccessMulti-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells
Chronic hepatitis B virus (HBV) infection is partly responsible for hepatitis, fatty liver disease and hepatocellular carcinoma (HCC). HBV core protein (HBc), encoded by the HBV genome, may play a significant ...
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Article
Open AccessUltrathin electronic synapse having high temporal/spatial uniformity and an Al2O3/graphene quantum dots/Al2O3 sandwich structure for neuromorphic computing
An electronic synapse (e-synapse) based on memristive switching is a promising electronic element that emulates a biological synapse to realize neuromorphic computing. However, the complex resistive switching ...
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Open AccessInkjet-printed unclonable quantum dot fluorescent anti-counterfeiting labels with artificial intelligence authentication
An ideal anti-counterfeiting technique has to be inexpensive, mass-producible, nondestructive, unclonable and convenient for authentication. Although many anti-counterfeiting technologies have been developed, ...
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Open AccessFactors affecting bone maturation in Chinese girls aged 4–8 years with isolated premature thelarche
In isolated premature thelarche (IPT) girls, bone age (BA) is considered consistent with chronological age. However, some IPT girls confirmed by gonadotropin-releasing hormone (GnRH) stimulation test could sho...
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Open AccessTwo major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance
A breach of T cell tolerance is considered as a major step in the pathogenesis of rheumatoid arthritis. In collagen-induced arthritis (CIA) model, immunization with type II collagen (COL2) leads to arthritis i...
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Open AccessTwo cases of infantile-onset primary generalized glucocorticoid hypersensitivity and the effect of mifepristone
Primary generalized glucocorticoid hypersensitivity (PGGH) is a very rare disease caused by terminal organ hypersensitivity to glucocorticoids for which the aetiology is unknown. The incidence of PGGH is extre...
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Open AccessDual-function perovskite light-emitting/sensing devices for optical interactive display
Interactive display devices integrating multiple functions have become a development trend of display technology. The excellent luminescence properties of perovskite quantum dots (PQDs) make it an ideal lumine...
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Open AccessA subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Rheumatoid arthritis (RA) involves several classes of pathogenic autoantibodies, some of which react with type-II collagen (COL2) in articular cartilage. We previously described a subset of COL2 antibodies tar...