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  1. No Access

    Article

    TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1

    Resistance to temozolomide (TMZ) remains an important cause of treatment failure in patients with glioblastoma multiforme (GBM). TRIM25, as a tripartite motif-containing (TRIM) family member, plays a significa...

    Jianwei Wei, Li Wang, Yuyan Zhang, Ting Sun, Cai Zhang, Zhonglan Hu… in Oncogene (2023)

  2. Article

    Open Access

    SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction

    Defective execution of proteases and protease inhibitors that mediate abnormal signaling cascades is emerging as a key contributor to skin diseases, such as psoriasis. SerpinB7 is identified as a skin-specific...

    Hua** Zheng, Linna Gu, Fulei Zhao, Chen Zhang, Zhen Wang… in Cell Death & Disease (2022)

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