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  1. No Access

    Article

    Smoke Control Strategy and Design Criterion in Tunnel Fire Hazards Using Point Extraction Ventilation: Experimental Analysis and Theoretical Modeling

    The hot and toxic smoke is a major reason for deaths and injuries in tunnel fire hazards, therefore, it is of vital importance for safe evacuation to effectively control the smoke. This paper proposed a smoke ...

    Peng Zhao, Zhongyuan Yuan, Chenchen Liang, Yan** Yuan, Rui Wang in Fire Technology (2024)

  2. Article

    Open Access

    Designed wrinkles for optical encryption and flexible integrated circuit carrier board

    Patterns on polymers usually have different mechanical properties as those of the substrates, causing deformation or distortion and even detachment of the patterns from the polymer substrates. Herein, we prese...

    Shilong Zhong, Zhaoxiang Zhu, Qizheng Huo, Yubo Long, Li Gong in Nature Communications (2024)

  3. No Access

    Article

    ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway

    Refractory wounds are a severe complication of diabetes mellitus that often leads to amputation because of the lack of effective treatments and therapeutic targets. The pathogenesis of refractory wounds is com...

    Tianru Huyan, Lu Fan, Zhong-yuan Zheng, **g-hui Zhao in Acta Pharmacologica Sinica (2024)

  4. No Access

    Article

    Nicotinamide Riboside Promotes the Proliferation of Endogenous Neural Stem Cells to Repair Spinal Cord Injury

    Activation of endogenous neural stem cells (NSC) is one of the most potential measures for neural repair after spinal cord injury. However, methods for regulating neural stem cell behavior are still limited. H...

    Jian** Zhang, Jun Shang, Han Ding, Wenxiang Li in Stem Cell Reviews and Reports (2024)

  5. Article

    Open Access

    The abnormalities of free fatty acid metabolism in patients with hypertrophic cardiomyopathy, a single-center retrospective observational study

    Previous studies have shown the importance of energy deficiency and malfunctioning mitochondria in the pathophysiology of hypertrophic cardiomyopathy (HCM). There has been a little research into the relationsh...

    Ke Zhang, Zhongyu Yuan, Shengwei Wang, Shifeng Zhao in BMC Cardiovascular Disorders (2024)

  6. Article

    Open Access

    Pyrotinib and trastuzumab plus palbociclib and fulvestrant in HR+/HER2+ breast cancer patients with brain metastasis

    Human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) patients are at a high risk of develo** metastases in the brain. However, research focusing on treatment strategies for hormonal r...

    Dongshao Chen, Fei Xu, Yongkui Lu, Wen **a, Caiwen Du, Dun **ong in npj Breast Cancer (2024)

  7. No Access

    Article

    Active tectonic deformation and its seismic–geological significance of boundary faults of the Daxing Uplift and Langgu–Dachang Depression, Bei**g Plain, China

    Boundary faults of the Daxing Uplift and Langgu–Dachang Depression are located in the southeastern region of the Bei**g Plain and directly control the sedimentation, tectonic evolution, and strong seismic act...

    Rong-Ying Zheng, Zhong-Yuan Yu, Bai-Xu Chen, Lu-Wei Li, Yi-Cheng Wang in Applied Geophysics (2024)

  8. Article

    Correction: Incorporating Prior Data in Quantitative Benefit–Risk Assessments: Case Study of a Bayesian Method

    Sai Dharmarajan PhD, Zhong Yuan MD, PhD in Therapeutic Innovation & Regulatory Science (2024)

  9. No Access

    Article

    Incorporating Prior Data in Quantitative Benefit–Risk Assessments: Case Study of a Bayesian Method

    Multiple criteria decision analysis (MCDA) and stochastic multi-criteria acceptability analysis (SMAA) in their current implementation cannot incorporate prior or external information on benefits and risks. We...

    Sai Dharmarajan PhD, Zhong Yuan MD, PhD in Therapeutic Innovation & Regulatory Science (2024)

  10. Article

    Open Access

    A multifunctional display based on photo-responsive perovskite light-emitting diodes

    Current display screens are typically only used for information display, but can have a range of different sensors integrated into them for functions such as touch control, ambient light sensing and fingerprin...

    Chunxiong Bao, Zhongcheng Yuan, Wenxiao Niu, Jie Yang, Zijian Wang in Nature Electronics (2024)

  11. Article

    Open Access

    Genetic characterizations of Cryptosporidium spp. from children with or without diarrhea in Wenzhou, China: high probability of zoonotic transmission

    Cryptosporidium is a highly pathogenic parasite responsible for diarrhea in children worldwide. Here, the epidemiological status and genetic characteristics of Cryptosporidium in children with or without diarrhea...

    Wei Zhao, Guangxu Ren, Weiyan Jiang, Long Wang, Jiayang Wang in BMC Microbiology (2024)

  12. Article

    Open Access

    Renal interstitial fibrotic assessment using non-Gaussian diffusion kurtosis imaging in a rat model of hyperuricemia

    To investigate the feasibility of Diffusion Kurtosis Imaging (DKI) in assessing renal interstitial fibrosis induced by hyperuricemia.

    **-Kang Chen, Zhong-Yuan Cheng, Ya-Lin Wang, Bao-Jun Xu in BMC Medical Imaging (2024)

  13. No Access

    Article

    PAH Pollution in Particulate Matter and Risk in Chinese Cities

    In China, with the largest population and known as the world's factory, the study of air pollution trends can provide an important reference value for the world's population and manufacturing countries. In par...

    Yongfu Wu, Ning Zhang, Yan Shi, Zetao Chen, Han Zhang, Jiaqiang Yin in Exposure and Health (2024)

  14. No Access

    Article

    A Constitutive Model for Softening Behaviors of Skin Tissue

    Skin tissue is a kind of complex biological material abundant with fibers. A new constitutive model, relating macroscopic responses with microstructural fiber configuration alteration, is developed to investig...

    Zhonghui Yuan, Zheng Zhong in Acta Mechanica Solida Sinica (2024)

  15. Article

    Open Access

    Predicting pathological complete response to neoadjuvant chemotherapy in breast cancer patients: use of MRI radiomics data from three regions with multiple machine learning algorithms

    To construct a multi-region MRI radiomics model for predicting pathological complete response (pCR) in breast cancer (BCa) patients who received neoadjuvant chemotherapy (NACT) and provide a theoretical basis ...

    Guangying Zheng, Jiaxuan Peng, Zhenyu Shu in Journal of Cancer Research and Clinical On… (2024)

  16. No Access

    Article

    Al-enabled properties distribution prediction for high-pressure die casting Al-Si alloy

    High-pressure die casting (HPDC) is one of the most popular mass production processes in the automotive industry owing to its capability for part consolidation. However, the nonuniform distribution of mechanic...

    Yu-Tong Yang, Zhong-Yuan Qiu, Zhen Zheng, Liang-** Pu in Advances in Manufacturing (2024)

  17. No Access

    Article

    Pyrolysis Empirical Modeling of Polyester Glass Fiber Reinforced Plastics Using Sestak-Berggren Model Method

    Polyester Glass Fiber Reinforced Plastic (Polyester GFRP), a thermosetting plastic comprised of glass fiber and polyester polymer compounds, is extensively utilized in high-speed trains. Unraveling its pyrolys...

    Wei Nan, Wenhui Ji, Yan** Yuan, Zhongyuan Yuan, Yong Sun in Journal of Thermal Science (2024)

  18. Article

    Open Access

    Prognostic factors in extensive-stage small cell lung cancer patients with organ-specific metastasis: unveiling commonalities and disparities

    This study aimed to identify shared and distinct prognostic factors related to organ-specific metastases (liver, lung, bone, and brain) in extensive-stage small cell lung cancer (ES-SCLC) patients, then constr...

    Yuanli Wu, **g Zhang, Weiying Zhou in Journal of Cancer Research and Clinical On… (2024)

  19. No Access

    Article

    Effects of Brown Fishmeal on Growth Performance, Digestibility, and Lipid Metabolism of the Chinese Soft-Shelled Turtle (Pelodiscus sinensis)

    The aim of this study was to evaluate the effect of brown fishmeal in replacement of white fishmeal in the diet of Chinese soft-shelled turtles and to find the optimal amount of brown fishmeal to add. Five exp...

    Guo-Fang Zhong, Liang-Fa Zhang, Yi Zhuang, Qi Li, He Huang in Marine Biotechnology (2024)

  20. No Access

    Article

    Conditional transcriptome-wide association study for fine-map** candidate causal genes

    Transcriptome-wide association studies (TWASs) aim to integrate genome-wide association studies with expression-map** studies to identify genes with genetically predicted expression (GReX) associated with a ...

    Lu Liu, Ran Yan, ** Guo, Jiadong Ji, Weiming Gong, Fuzhong Xue in Nature Genetics (2024)

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