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  1. Article

    Open Access

    Physics-informed shape optimization using coordinate projection

    The rapid growth of artificial intelligence is revolutionizing classical engineering society, offering novel approaches to material and structural design and analysis. Among various scientific machine learning...

    Zhizhou Zhang, Chungwei Lin, Bingnan Wang in Scientific Reports (2024)

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  2. No Access

    Article

    Deformable multi-scale fusion network for non-uniform single image deblurring

    Non-uniform image deblurring is an ill-posed problem. Previous research efforts attempt to solve this problem by increasing the number of scales processed in the model, including but not limited to multi-scale...

    Zhizhou Zhang, Yang Chen, Aichun Zhu, Hanxi Liu in Multimedia Tools and Applications (2023)

  3. No Access

    Article

    Ultrasensitive colorimetric strategy for Hg2+ detection based on T-Hg2+-T configuration and target recycling amplification

    A novelty aptasensor for ultrasensitive detection of Hg2+ is developed, exploiting the combination of plasmonic properties of gold nanoparticles (AuNPs) and exonuclease III (Exo III)-assisted target recycling for...

    Fuming Sang, Suyao Yin, Jianxin Pan… in Analytical and Bioanalytical Chemistry (2021)

  4. No Access

    Article

    Colorimetric determination of DNA using an aptamer and plasmonic nanoplatform

    A facile plasmonic nanoplatform was developed for rapid and sensitive determination of nucleic acid. Hg2+-regulated molecular beacon (MB, hairpin) containing rich thymine (T) bases at both ends is used as the pro...

    Fuming Sang, Suyao Yin, Jianxin Pan, Deli Liu, Zhizhou Zhang in Microchimica Acta (2020)

  5. No Access

    Article

    A hairpin-type DNA probe for direct colorimetric detection of endonuclease activity and inhibition based on the deaggregation of gold nanoparticles

    A method is described for the determination of the activity of endonuclease. It based on the deaggregation of gold nanoparticles (AuNPs) aggregated by the action of poly(diallyldimethylammonium chloride) (PDDA...

    Fuming Sang, Guoliang Li, Jun Li, Jianxin Pan, Zhizhou Zhang… in Microchimica Acta (2019)

  6. Article

    Open Access

    A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

    A long-standing belief is that aging (senescence) is the result of stochastic damage accumulation. Alternatively, senescent pathology may also result from late-life, wild-type gene action (i.e., antagonistic p...

    Hongyuan Wang, Yuan Zhao, Marina Ezcurra… in npj Aging and Mechanisms of Disease (2018)

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  7. No Access

    Article

    Employment of Near Full-Length Ribosome Gene TA-Cloning and Primer-Blast to Detect Multiple Species in a Natural Complex Microbial Community Using Species-Specific Primers Designed with Their Genome Sequences

    It remains an unsolved problem to quantify a natural microbial community by rapidly and conveniently measuring multiple species with functional significance. Most widely used high throughput next-generation se...

    Huimin Zhang, Hongkui He, **ujuan Yu, Zhaohui Xu, Zhizhou Zhang in Molecular Biotechnology (2016)

  8. No Access

    Article

    Anti-biofouling property studies on carboxyl-modified multi-walled carbon nanotubes filled PDMS nanocomposites

    Polydimethylsiloxane (PDMS) with exceptional fouling-release properties is extremely susceptible to the microfouling resulted from the colonization of the pioneer microorganisms in the marine environment. In t...

    Yuan Sun, Zhizhou Zhang in World Journal of Microbiology and Biotechnology (2016)

  9. No Access

    Article

    CdTe Quantum Dots Enhance Feasibility of EvaGreen-Based Real-Time PCR with Decent Amplification Fidelity

    Quantitative real-time PCR (qPCR), as an important quantitative technique for nucleic acids, has been widely used in many fields including clinical diagnosis, molecular biology, and cancer research. However, n...

    Fuming Sang, Zhizhou Zhang, Zhong Xu, **aolei Ju, Hongyuan Wang… in Molecular Biotechnology (2013)

  10. No Access

    Article

    Double Hopf bifurcation of time-delayed feedback control for maglev system

    This paper undertakes an analysis of a double Hopf bifurcation of a maglev system with time-delayed feedback. At the intersection point of the Hopf bifurcation curves in velocity feedback control gain and time...

    Lingling Zhang, Zhizhou Zhang, Lihong Huang in Nonlinear Dynamics (2012)

  11. No Access

    Article

    Stability and Hopf bifurcation of the maglev system with delayed position and speed feedback control

    In this paper, the dynamic behavior of suspension system of maglev train with time-delayed position and velocity feedback signal is considered with rigid guideway. The stability conditions of the system are ob...

    Lingling Zhang, Lihong Huang, Zhizhou Zhang in Nonlinear Dynamics (2009)

  12. No Access

    Article

    DNA addition using linear self-assembly

    This paper presents a DNA algorithm which adds two nonnegative binary integers using self-assembly in constant steps. The approach has the benefit of greater experimental simplicity when compared with previous...

    Jian Zhao, LuLu Qian, Qiang Liu, ZhiZhou Zhang, Lin He in Chinese Science Bulletin (2007)

  13. No Access

    Chapter and Conference Paper

    An Implementation for Map** SBML to BioSPI

    The Systems Biology Markup Language(SBML) is an XML-based format for representing models of Systems Biology. BioSPI is a formal model to simulate biological systems, which is evolved from process calculi. Base...

    Zhupeng Dong, **aoju Dong, **an Xu, Yuxi Fu… in Fuzzy Systems and Knowledge Discovery (2005)

  14. No Access

    Chapter and Conference Paper

    Convergence Analysis of Genetic Regulatory Networks Based on Nonlinear Measures

    In this paper, we propose a nonlinear 2-measure concept, and using it, together with the nonlinear 1-measure proposed earlier by other researchers, to analyze the global convergence of genetic regulatory netwo...

    Hongtao Lu, Zhizhou Zhang, Lin He in Advances in Neural Networks – ISNN 2005 (2005)

  15. No Access

    Chapter and Conference Paper

    Representation of the Signal Transduction with Aberrance Using Ipi Calculus

    The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interference pi calculus, is introduced...

    Min Zhang, Guoqiang Li, Yuxi Fu, Zhizhou Zhang… in Computational and Information Science (2005)

  16. No Access

    Article

    Linearly programmed DNA-based molecular computer operated on magnetic particle surface in test-tube

    The postgenomic era has seen an emergence of new applications of DNA manipulation technologies, including DNA-based molecular computing. Surface DNA computing has already been reported in a number of studies t...

    Jian Zhao, Zhizhou Zhang, Yongyong Shi, **uxia Li, Lin He in Chinese Science Bulletin (2004)

  17. No Access

    Article

    Mechanism of enhancement of prochymosin renaturation by solubilization of inclusion bodies at alkaline pH

    The renaturation efficiency of recombinant prochymosin depends on not only the renaturation conditions but also the solubilization (denaturation) conditions. Compared with pH 8, solubilization of prochymosin-c...

    Zhizhou Zhang, Yuying Zhang, Kaiyu Yang in Science in China Series C: Life Sciences (1997)