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Open AccessEffect of bridge height on airflow and aeolian sand flux near surface along the Qinghai-Tibet Railway, China
In this work, we studied the near-surface flow field structure of railway bridges with different heights through field investigation and wind tunnel simulation experiments. Meanwhile, we simulated the distribu...
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Article
Open AccessSynthesis of borocarbonitride nanosheets from biomass for enhanced charge separation and hydrogen production
Borocarbonitride (BCN) materials have shown significant potential as photocatalysts for hydrogen production. However, traditional bulk BCN exhibits only moderate photocatalytic activity. In this study, we intr...
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Article
Open AccessOne-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China
The accelerated growth of older individuals worldwide has increased the number of patients presenting with fragility hip fractures. Having a hip fracture can cause excess mortality, and patients with hip fract...
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Open AccessPsychometric validation of the Chinese versions of the quality of communication questionnaires for cancer patients and their family caregivers
Given the lack of valid and reliable instruments for evaluating the quality of communication between physicians and cancer patients and their family caregivers in China, this study translated and culturally ad...
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Article
Open AccessOrganization of corticocortical and thalamocortical top-down inputs in the primary visual cortex
Unified visual perception requires integration of bottom-up and top-down inputs in the primary visual cortex (V1), yet the organization of top-down inputs in V1 remains unclear. Here, we used optogenetics-assi...
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Open AccessOrganocatalytic skeletal reorganization for enantioselective synthesis of S-stereogenic sulfinamides
The enantioselective synthesis of S-stereogenic sulfinamides has garnered considerable attention due to their structural and physicochemical properties. However, catalytic asymmetric synthesis of sulfinamides sti...
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Article
Open AccessFine-map** analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unkn...
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Article
Open AccessClinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study
The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-known. Accordingly, this study investigated the clinical characteristics of IOS-BDR and ...
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Article
Open AccessDecreasing exciton dissociation rates for reduced voltage losses in organic solar cells
Enhancing the device electroluminescence quantum efficiency (EQEEL) is a critical factor in mitigating non-radiative voltage losses (VNR) and further improving the performance of organic solar cells (OSCs). While...
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Article
Correction to: AA-forecast: anomaly-aware forecast for extreme events
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Open AccessIdentification of a novel macrophage-related prognostic signature in colorectal cancer
Colorectal cancer (CRC) is one of the most prevalent and deadliest illnesses all around the world. Growing proofs demonstrate that tumor-associated macrophages (TAMs) are of critical importance in CRC pathogen...
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Article
Open AccessNeutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages
The tumor microenvironment is reprogrammed by cancer cells and participates in all stages of tumor progression. Neutral ceramidase is a key regulator of ceramide, the central intermediate in sphingolipid metab...
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Article
Open AccessPossible melatonin-induced salt stress tolerance pathway in Phaseolus vulgaris L. using transcriptomic and metabolomic analyses
Melatonin plays important roles in multiple stress responses; however, the downstream signaling pathway and molecular mechanism remain unclear. This study aimed to elucidate the transcriptional regulation of m...
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Open AccessCombining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European a...
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Open AccessScheduling IDK classifiers with arbitrary dependences to minimize the expected time to successful classification
This paper introduces and evaluates a general construct for trading off accuracy and overall execution duration in classification-based machine perception problems—namely, the generalized IDK classifier cascade. ...
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Article
Open AccessDevelopment and validation of a nomogram based on common biochemical indicators for survival prediction of children with high-risk neuroblastoma: A valuable tool for resource-limited hospitals
Despite multiple attempts have been made to develop risk stratification within high-risk neuroblastoma (NB) patients (age of diagnosis ≥ 18 month-old with metastatic NB), the definition of “ultra high-risk NB”...
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Open AccessEnantioselective organocatalytic synthesis of axially chiral aldehyde-containing styrenes via SNAr reaction-guided dynamic kinetic resolution
The precise and efficient construction of axially chiral scaffolds, particularly toward the aryl-alkene atropoisomers with impeccably full enantiocontrol and highly structural diversity, remains greatly challe...
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Article
Open AccessStudy on tide characteristics and mechanism of PSP in buried pipeline along the lake
The fluctuations of the Pipe-to-Soil Potential (PSP) in buried pipes are influenced by the geoelectric field induced by changes in the Earth's magnetic field, which can accelerate pipeline corrosion. Monitorin...
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Open AccessEnantioconvergent construction of stereogenic silicon via Lewis base-catalyzed dynamic kinetic silyletherification of racemic chlorosilanes
Organosilanes possessing an enantioenriched stereogenic silicon center are important in many branches of chemistry, yet they remain challenging to synthesize in a practical and scalable way. Here we report a d...
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Open AccessCorrection: Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking