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Open AccessOne-year mortality risk in older individuals with femoral intertrochanteric fracture: a tertiary center in China
The accelerated growth of older individuals worldwide has increased the number of patients presenting with fragility hip fractures. Having a hip fracture can cause excess mortality, and patients with hip fract...
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Open AccessPsychometric validation of the Chinese versions of the quality of communication questionnaires for cancer patients and their family caregivers
Given the lack of valid and reliable instruments for evaluating the quality of communication between physicians and cancer patients and their family caregivers in China, this study translated and culturally ad...
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Open AccessClinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study
The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-known. Accordingly, this study investigated the clinical characteristics of IOS-BDR and ...
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Open AccessDevelopment and validation of a nomogram based on common biochemical indicators for survival prediction of children with high-risk neuroblastoma: A valuable tool for resource-limited hospitals
Despite multiple attempts have been made to develop risk stratification within high-risk neuroblastoma (NB) patients (age of diagnosis ≥ 18 month-old with metastatic NB), the definition of “ultra high-risk NB”...
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Open AccessCorrection: Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
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Open AccessPregnancy feasibility in women with mild pulmonary arterial hypertension: a systematic review and meta-analysis
The aim of this study was to evaluate the pregnancy feasibility of women with mild pulmonary hypertension according to pregnancy outcomes.
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Open AccessExploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
Yinzhihuang granules (YZHG) is a commonly used Chinese patent medicine for the treatment of liver disease. However, the mechanism of YZHG in alcoholic liver disease (ALD) is still unclear.
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Open AccessTrochanteric and subtrochanteric fractures irreducible by closed reduction: a retrospective study
To explore the preoperative radiographic features and reduction methods of irreducible trochanteric and subtrochanteric fractures of the femur and to compare the perioperative characteristics and prognoses of ...
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Open AccessClinical characteristics of airway impairment assessed by impulse oscillometry in patients with chronic obstructive pulmonary disease: findings from the ECOPD study in China
The role of airway impairment assessed by impulse oscillometry (IOS) in patients with chronic obstructive pulmonary disease (COPD) remains unclear. Therefore, this study aimed to analyze the proportion and cli...
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Open AccessAssociation between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation
The objective of this study was to investigate the relationship between P2Y1 and P2Y12 genotypes and the risk of acute myocardial infarction (AMI) in the Quanzhou population and to determine associations betwe...
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Open AccessIdentification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments
Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly und...
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Open AccessPreserved ratio impaired spirometry is associated with small airway dysfunction and reduced total lung capacity
Preserved ratio impaired spirometry (PRISm) refers to decreased forced expiratory volume in 1 s (FEV1) in the setting of preserved ratio. Little is known about the role of PRISm and its complex relation with smal...
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Open AccessSysmex UN2000 detection of protein/creatinine ratio and of renal tubular epithelial cells can be used for screening lupus nephritis
This study is aimed to evaluate if automated urine sediment analysis UN2000 can be used to screen lupus nephritis.
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Open AccessConstruction of machine learning tools to predict threatened miscarriage in the first trimester based on AEA, progesterone and β-hCG in China: a multicentre, observational, case-control study
Endocannabinoid anandamide (AEA), progesterone (P4) and β-human chorionic gonadotrophin (β-hCG) are associated with the threatened miscarriage in the early stage. However, no study has investigated whether com...
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Open AccessThe association between small airway dysfunction and aging: a cross-sectional analysis from the ECOPD cohort
Aging has been evidenced to bring about some structural and functional lung changes, especially in COPD. However, whether aging affects SAD, a possible precursor of COPD, has not been well characterized.
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Open AccessValidity of a portable spirometer in the communities of China
The lack of simple and affordable spirometry has led to the missed and delayed diagnoses of chronic respiratory diseases in communities. The PUS201P is a portable spirometry developed to solve this problem.
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Open AccessCharacteristics of intramedullary nail breakage in pertrochanteric femur fractures: a summary of 70 cases
To reveal noteworthy characteristics of intramedullary (IM) nail breakage in pertrochanteric femur fractures.
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Open AccessGut microbiota dysbiosis contributes to the development of chronic obstructive pulmonary disease
Dysbiosis of the gut microbiome is involved in the pathogenesis of various diseases, but the contribution of gut microbes to the progression of chronic obstructive pulmonary disease (COPD) is still poorly unde...
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Open AccessPsychopathological symptom network structure in transgender and gender queer youth reporting parental psychological abuse: a network analysis
This is the first study to investigate the effect of parental psychological abuse on potential psychopathological symptoms in gender minority youth subgroups, including transgender women, transgender men, and ...
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Open AccessClinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
Limited studies were available to investigate the prevalence of deep vein thrombosis (DVT) on admission in elderly patients with intertrochanteric fractures. The aim of present study was to evaluate risk facto...