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  1. Article

    Open Access

    Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype

    Non-cystic fibrosis bronchiectasis is a chronic respiratory disease characterized by bronchial dilation. However, the significance of elevated eosinophil counts in acute exacerbations of bronchiectasis remains...

    Weixin Chen, Siyi Ran, Chenchang Li, Zhixin Li, Nili Wei, **g Li, Naijian Li in Lung (2024)

  2. Article

    Open Access

    Gut microbiota dysbiosis contributes to the development of chronic obstructive pulmonary disease

    Dysbiosis of the gut microbiome is involved in the pathogenesis of various diseases, but the contribution of gut microbes to the progression of chronic obstructive pulmonary disease (COPD) is still poorly unde...

    Naijian Li, Zhouli Dai, Zhang Wang, Zhishan Deng, Jiahuan Zhang in Respiratory Research (2021)

  3. Article

    Open Access

    Positive change in asthma control using therapeutic patient education in severe uncontrolled asthma: a one-year prospective study

    Severe asthma is difficult to control. Therapeutic patient education enables patients to better understand their disease and cope with treatment, but the effect of therapeutic patient education in severe uncon...

    **aoxian Zhang, Zhengdao Lai, Rihuang Qiu, E Guo, **g Li in Asthma Research and Practice (2021)

  4. Article

    Open Access

    Chronic exposure to ambient particulate matter induces gut microbial dysbiosis in a rat COPD model

    The role of the microbiota in the pathogenesis of chronic obstructive pulmonary disease (COPD) following exposure to ambient particulate matter (PM) is largely unknown.

    Naijian Li, Zhaowei Yang, Baoling Liao, Tianhui Pan, **ding Pu in Respiratory Research (2020)

  5. Article

    Open Access

    Exposure to ambient particulate matter alters the microbial composition and induces immune changes in rat lung

    Ambient particulate matter exposure has been shown to increase the risks of respiratory diseases. However, the role of the lung microbiome and the immune response to inhaled particulate matter are largely unex...

    Naijian Li, Fang He, Baoling Liao, Yuming Zhou, Bing Li, Pixin Ran in Respiratory Research (2017)

  6. Article

    Open Access

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin in World Allergy Organization Journal (2016)