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  1. No Access

    Article

    Tortuosity regulation of two-dimensional nanofluidic films for water evaporation-induced electricity generation

    Water evaporation-induced electricity generation is a promising technology for renewable energy harvesting. However, the output power of some reported two-dimensional (2D) nanofluidic films is still restricted...

    Zhihang Liu, Chao Liu, Anqi Ni, Kunpeng Mao, Long Chen, Liang Xue in Nano Research (2024)

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    Article

    Three-year outcomes of transanal total mesorectal excision versus standard laparoscopic total mesorectal excision for mid and low rectal cancer

    Since transanal total mesorectal excision (taTME) was introduced, it has become an important topic in rectal cancer treatment. Many previous studies reported positive relevant short-term results, histopatholog...

    Ziwei Zeng, Zhihang Liu, Shuangling Luo, Zhenxing Liang, Liang Huang in Surgical Endoscopy (2022)

  3. Article

    Open Access

    Fibroblast growth factor-21 as a novel metabolic factor for regulating thrombotic homeostasis

    Fibroblast growth factor-21 (FGF-21) performs a wide range of biological functions in organisms. Here, we report for the first time that FGF-21 suppresses thrombus formation with no notable risk of bleeding. P...

    Shuai Li, Haibo Jia, Zhihang Liu, Nan Wang, **aochen Guo, Muhua Cao in Scientific Reports (2022)

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    Article

    An immuno-blocking agent targeting IL-1β and IL-17A reduces the lesion of DSS-induced ulcerative colitis in mice

    In recent decades when biological agents have flourished, a part of patients suffering from inflammatory bowel disease (IBD) have received the treatment of tumor necrosis factor inhibitors or IL-1 antibodies. ...

    Qi Yin, Xuelei Pi, Yuanyuan Jiang, Gui** Ren, Zhihang Liu, Han Liu in Inflammation (2021)

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    Article

    Fibroblast Growth Factor–21 Ameliorates Rheumatoid Arthritis by Maintaining Articular Integrity

    Rheumatoid arthritis, a chronic degenerative autoimmune disease is hallmarked by tenacious inflammation of synovial membranes causing cartilage destruction and bone erosion. The search for effective therapies ...

    Yeboah Kwaku Opoku, Zhihang Liu, Han Liu in International Journal of Peptide Research … (2020)

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    Article

    Therapeutic Role of Fibroblast Growth Factor 21 (FGF21) in the Amelioration of Chronic Diseases

    Fibroblast growth factor-21 (FGF21) is a member of the family of fibroblast growth factors (FGFs). FGF21 (synthesized by many organs) has been studied extensively for its role in the regulation of energy homeo...

    Yeboah Kwaku Opoku, Zhihang Liu in International Journal of Peptide Research … (2020)

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    Article

    Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin–lactoferrampin alleviates the development of acute colitis in mice

    Ulcerative colitis (UC) is a chronic relapsing disease. Treatment of UC would benefit from specific targeting of therapeutics to the intestine. Previous studies have demonstrated that bovine lactoferricin and ...

    Liying Song, Weichun **e, Zhihang Liu, Dian Guo in Applied Microbiology and Biotechnology (2019)

  8. Article

    Open Access

    The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20

    Long noncoding RNAs (lncRNAs) have been emerging as master regulators of tumor growth and metastasis, but the functions and underlying mechanisms of lncRNAs in colorectal cancer (CRC) still need to be clarifie...

    **hu Yu, Zixu Yuan, Zuli Yang, Daici Chen, Taewan Kim, Yanmei Cui in Cell Death & Disease (2018)

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    Article

    Long-Term Administration of Fibroblast Growth Factor 21 Prevents Chemically-Induced Hepatocarcinogenesis in Mice

    In this study, we explored whether treatment with FGF-21 could prevent diethylnitrosamine (DEN) induced hepatocarcinogenesis in mice.

    Pengfei Xu, Yingjie Zhang, Wenfei Wang, Qingyan Yuan in Digestive Diseases and Sciences (2015)