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  1. Article

    Open Access

    Neutrophil extracellular trap-associated risk index for predicting outcomes and response to Wnt signaling inhibitors in triple-negative breast cancer

    Triple-negative breast cancer (TNBC) is a type of breast cancer with poor prognosis, which is prone to distant metastasis and therapy resistance. The presence of neutrophil extracellular traps (NETs) contribut...

    Zhidong Huang, **hui Wang, Bo Sun, Mengyang Qi, Shuang Gao, Hong Liu in Scientific Reports (2024)

  2. No Access

    Article

    Long-term efficacy and safety of leflunomide combined with low-dose prednisone in treatment of myasthenia gravis: a retrospective study

    Leflunomide and low-dose prednisone (0.25 mg/kg/day) (LEF + Pred) rapidly improved the clinical symptoms of myasthenia gravis (MG) patients. Here, we aimed to analyze the long-term efficacy and safety of LEF +...

    Li Qiu, Pei Chen, Changyi Ou, Juan Deng, Zhidong Huang in Acta Neurologica Belgica (2024)

  3. No Access

    Article

    Association of malnutrition with all-cause and cardiovascular mortality in patients with mild to severe chronic kidney disease undergoing coronary angiography: a large multicenter longitudinal study

    Evidence on the prognostic impact of malnutrition was focused on patients with advanced kidney disease. The relationships between malnutrition and all-cause and cardiovascular mortality in patients with differ...

    Fei Gao, Zhidong Huang, **g**g Liang, Yu Kang in International Urology and Nephrology (2023)

  4. No Access

    Article

    Predictors of mortality in heart failure with reduced ejection fraction: interaction between diabetes mellitus and impaired renal function

    The harmful effect of diabetes mellitus (DM) on mortality in patients with heart failure with reduced ejection fraction (HFrEF) remains controversial. Furthermore, it seems that no consistent conclusion on whe...

    Yanfang Yang, Zhidong Huang, Bo Wu, ** Lu in International Urology and Nephrology (2023)

  5. No Access

    Article

    Association of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and acute kidney disease in patients undergoing coronary angiography: a cohort study

    Acute kidney disease (AKD) following coronary angiography (CAG) indicates a higher risk of chronic kidney disease and follow-up cardiovascular comorbidities. However, the predictive risk factor of AKD is not c...

    Yihang Ling, Yibo He, Wei Guo, Rongting Zhang in International Urology and Nephrology (2023)

  6. No Access

    Chapter and Conference Paper

    PU Matrix Completion Based Multi-label Classification with Missing Labels

    Multi-label classification has attracted significant interests in various domains. However, only few positive labels are labeled. Treating unknown labels as negative labels brings the one-side noise, which cau...

    Zhidong Huang, Peipei Li, Xuegang Hu in Intelligent Systems Design and Applications (2023)

  7. Article

    Open Access

    M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma

    N7-Methylguanosine (m7G) and long non-coding RNAs (lncRNAs) have been widely studied in cancer and have been found to be useful for assessing tumor progression. However, the role of m7G-related lncRNAs in lung...

    Junfan Pan, Zhidong Huang, Hancui Lin, Wenfang Cheng, **huo Lai in BMC Cancer (2022)

  8. Article

    Open Access

    The association between prothrombin time-international normalized ratio and long-term mortality in patients with coronary artery disease: a large cohort retrospective study with 44,662 patients

    The association between prothrombin time-international normalized ratio (PT-INR) and long-term prognosis among patients with coronary artery disease (CAD) without atrial fibrillation or anticoagulant therapy w...

    Liwei Liu, Ming Ying, Shiqun Chen, Qiang Li, Guanzhong Chen in BMC Cardiovascular Disorders (2022)

  9. No Access

    Article

    Prevalence and mortality of transient acute kidney injury within 48 h, as new subtype, following coronary angiography: a cohort study

    The association of transient acute kidney injury (AKI) with mortality was controversial. Our study aims to investigate the prevalence and impact of transient AKI on mortality in patients following coronary ang...

    Qiang Li, Mengfei Lin, Haozhang Huang, Liwei Liu in Clinical and Experimental Nephrology (2022)

  10. No Access

    Article

    Malnutrition and the risk for contrast-induced acute kidney injury in patients with coronary artery disease

    Malnutrition is a common comorbidity of coronary artery disease (CAD) and is often associated with adverse events. The malnutrition often means lower cholesterol, albumin and high lymphocyte, as risk factors o...

    Liling Chen, Zhidong Huang, Weiguo Li, Yibo He in International Urology and Nephrology (2022)

  11. Article

    Open Access

    Platelet-to-hemoglobin ratio as a valuable predictor of long-term all-cause mortality in coronary artery disease patients with congestive heart failure

    The platelet-to-hemoglobin ratio (PHR) has emerged as a prognostic biomarker in coronary artery disease (CAD) patients after PCI but not clear in CAD complicated with congestive heart failure (CHF). Hence, we ...

    Kunming Bao, Haozhang Huang, Guoyong Huang, Junjie Wang in BMC Cardiovascular Disorders (2021)

  12. Article

    Open Access

    Independent and joint effects of high-sensitivity c-reactive protein and hypoalbuminemia on long-term all-cause mortality among coronary artery disease: a prospective and multicenter cohort study

    High-sensitivity C-reactive protein (hs-CRP) plays an important role in hypoalbuminemia as a representative of inflammation, which is closely associated with poor prognosis among patients with coronary artery ...

    Haozhang Huang, Yaren Yu, Liling Chen, Shiqun Chen in BMC Cardiovascular Disorders (2021)

  13. Article

    Open Access

    Prevalence and prognostic significance of malnutrition in diabetic patients with coronary artery disease: a cohort study

    Malnutrition is associated with poor prognosis in cardiovascular disease patients or in diabetic patients. However, the relationship between malnutrition and clinical outcomes in diabetic patients with coronar...

    Wen Wei, Lingyu Zhang, Guode Li, Zhidong Huang, ** Liu in Nutrition & Metabolism (2021)

  14. Article

    Open Access

    Predictive value of creatine kinase MB for contrast-induced acute kidney injury among myocardial infarction patients

    Predictive value of creatine kinase MB (CK-MB) for contrast-induced acute kidney injury (CI-AKI) among myocardial infarction (MI) patients has rarely been reported. We aim to evaluate the predictive value of C...

    Wen Wei, Lingyu Zhang, Yunhan Zhang, Ronghui Tang in BMC Cardiovascular Disorders (2021)

  15. Article

    Open Access

    Trends in incidence and long-term prognosis of acute kidney injury following coronary angiography in Chinese cohort with 11,943 patients from 2013 to 2017: an observational study

    Contrast-associated acute kidney injury (CA-AKI) is a common complication with poor prognosis after coronary angiography (CAG). With the prevention methods widely being implemented, the temporal trends of inci...

    ** Liu, Qiang Li, Disheng Lai, Guoqin Chen, Bo Wang, Liwei Liu in BMC Nephrology (2021)

  16. Article

    Open Access

    Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease

    Lower low-density lipoprotein cholesterol (LDL-C) is significantly associated with improved prognosis in patients with coronary artery disease (CAD). However, LDL-C reduction does not decrease all-cause mortal...

    Bo Wang, Shiqun Chen, ** Liu, Yan Liang, Liangguang Meng, **aoming Yan in BMC Nephrology (2021)

  17. Article

    Open Access

    Malnutrition affects cholesterol paradox in coronary artery disease: a 41,229 Chinese cohort study

    Several studies have found that a low baseline low -density lipoprotein cholesterol (LDL-C) concentration was associated with poor prognosis in patients with acute coronary syndrome (ACS), which is called the ...

    Bo Wang, ** Liu, Shiqun Chen, Ming Ying, Guanzhong Chen in Lipids in Health and Disease (2021)

  18. Article

    Open Access

    A comparison between two different definitions of contrast-associated acute kidney injury for long-term mortality in patients with diabetes undergoing coronary angiography: a prospective cohort study

    The definitions of contrast-associated acute kidney injury (CA-AKI) are diverse and have different predictive effects for prognosis, which are adverse for clinical practice. Few articles have discussed the rel...

    Zhubin Lun, Li Lei, Dianhua Zhou, Ming Ying, Liwei Liu in BMC Cardiovascular Disorders (2020)

  19. Article

    Open Access

    Population attributable risk estimates of risk factors for contrast-induced acute kidney injury following coronary angiography: a cohort study

    Contrast-induced acute kidney injury (CI-AKI) is a common complication with poor outcomes following coronary angiography (CAG) or percutaneous coronary intervention (PCI). However, no study has explored the po...

    Li Lei, Yan Xue, Zhaodong Guo, Bowen Liu, Yibo He in BMC Cardiovascular Disorders (2020)

  20. No Access

    Article

    Hospital and healthcare insurance system record–based epidemiological study of myasthenia gravis in southern and northern China

    This is the first cross-region epidemiological study of myasthenia gravis (MG) in China. We estimated the incidence, prevalence, and medical costs of MG in southern China and explored the differences between t...

    Wei Fang, Yan Li, Rong Mo, Jianjian Wang, Li Qiu, Chuangyi Ou in Neurological Sciences (2020)