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Article
Open AccessThe effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
The stimulant methylphenidate (MPH) and the non-stimulant atomoxetine (ATX) are frequently used for the treatment of attention-deficit/hyperactivity disorder (ADHD); however, the function of these drugs in dif...
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Article
How we do it? Performing a protective superficial temporal artery-middle cerebral artery bypass with endoscopic transnasal cavernous sinus lesion operation
To describe the concept of a protective superficial temporal artery-middle cerebral artery (STA-MCA) bypass performed prior to endoscopic transnasal cavernous sinus (CS) lesion resection in order to reduce the...
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Article
How we do it: the double keyhole micro-endoscopic combined complex pituitary adenoma surgery
Surgical removal of complex pituitary adenomas (PA) is a technically challenging procedure. To ensure safe and efficient surgery, we employ the micro-endoscopic combination technique.
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Article
How I do it? Surgical removal of a corpus callosum arteriovenous malformation using a robotic digital microscope
This report described the surgical nuance of a challenging deep-seated corpus callosum arteriovenous malformation (AVM) using a novel robotic digital microscope.
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Article
Ectopic pituitary adenomas: clinical features, diagnostic challenges and management
Ectopic pituitary adenomas (EPAs) are extremely rare pituitary adenomas located outside the sella turcica without any connection with intrasellar components. This study aims to review all the reported cases to...
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Article
Open AccessVariations in processes for guideline adaptation: a qualitative study of World Health Organization staff experiences in implementing guidelines
The World Health Organisation (WHO) publishes a large number of clinical practice and public health guidelines to promote evidence-based practice across the world. Due to the variety of health system capacitie...
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Article
Cosecreting TSH/GH pituitary adenomas—an 8-year experience in a single tertiary center
Thyrotropin-secreting pituitary adenoma is a rare disorder and was recently classified as an aggressive tumor in the World Health Organization guidelines. The number of available studies on cosecreting thyrotr...
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Article
Suprasellar pituitary adenomas: a 10-year experience in a single tertiary medical center and a literature review
Suprasellar pituitary adenomas (SPAs) are a special type of pituitary adenoma. Although dozens of SPA cases have been reported, the exact definition and the characteristics of SPA have not been exhaustively di...
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Article
Long-term follow-up for ectopic ACTH-secreting pituitary adenoma in a single tertiary medical center and a literature review
Ectopic ACTH-secreting pituitary adenoma (EAPA) are a rare cause of Cushing’s disease. Due to the lack of consensus and experience in terms of the diagnosis and treatment of EAPAs, preoperative identification...
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Article
Open AccessFirst report of Enterobacter hormaechei with respiratory disease in calves
Enterobacter hormaechei is commonly considered a causative pathogen for nosocomial infections and it does not usually cause diseases in animals. However, researchers have recently dissociated the pathogenic Enter...
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Article
Open AccessHealth promoter, advocate, legitimiser — the many roles of WHO guidelines: a qualitative study
Properly implemented evidence-based clinical and public health guidelines can improve patient outcomes. WHO has been a major contributor to guideline development, publishing more than 250 guidelines on various...
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Article
Open AccessPathological characteristics and genetic features of melanin-producing medullary thyroid carcinoma
To study the clinicopathological characteristics and genetic features of melanin-producing medullary thyroid carcinoma (MP-MTC).
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Article
Open AccessThe advantages and limitations of guideline adaptation frameworks
The implementation of evidence-based guidelines can improve clinical and public health outcomes by hel** health professionals practice in the most effective manner, as well as assisting policy-makers in desi...
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Article
Open AccessImplementation plans included in World Health Organisation guidelines
The implementation of high-quality guidelines is essential to improve clinical practice and public health. The World Health Organisation (WHO) develops evidence-based public health and other guidelines that ar...