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Open AccessDeep learning algorithm-based multimodal MRI radiomics and pathomics data improve prediction of bone metastases in primary prostate cancer
Bone metastasis is a significant contributor to morbidity and mortality in advanced prostate cancer, and early diagnosis is challenging due to its insidious onset. The use of machine learning to obtain prognos...
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Article
Open AccessSkeletal muscle extramedullary plasmacytoma transformed into plasmablastic plasmacytoma: a case report
Extramedullary plasmacytoma (EMP) is a rare plasma cell malignancy, especially when the tumor originates in skeletal muscle. Plasmablastic plasmacytoma is an anaplastic round cell tumor with highly malignancy ...
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Article
Risk prediction of second primary malignant tumor in primary differentiated thyroid cancer patients: a population-based study
To investigate the risk factors of second primary malignant tumor (SPMT) in patients with differentiated thyroid cancer (DTC) and establish a competing risk nomogram to predict the probability of SPMT occurrence.
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Early evaluation of severe immune checkpoint inhibitor-associated myocarditis: a real-world clinical practice
Immune checkpoint inhibitor (ICI)-associated myocarditis is a rare but severe complication for patients treated with immunotherapy. This study aims to explore the predictive significance of patients’ clinical ...
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Article
Characterization of immune exhaustion and suppression in the tumor microenvironment of splenic marginal zone lymphoma
The role of the tumor microenvironment (TME) and intratumoral T cells in splenic marginal zone lymphoma (sMZL) is largely unknown. In the present study, we evaluated 36 sMZL spleen specimens by single cell ana...
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Open AccessMechanism of salidroside against coronary artery disease by network pharmacology analysis
Rosenroot (Rhodiola rosea) is a traditional Chinese herbal medicine. It has been used to treat patients with coronary artery disease (CAD). Salidroside is the main active constituent of rosenroot. This study w...
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Open AccessExploring expectations of Chinese patients for total knee arthroplasty: once the medicine is taken, the symptoms vanish
Preoperative expectations of total knee arthroplasty (TKA) outcomes are important determinants of patient satisfaction. However, expectations of patients in different countries are affected by cultural backgro...
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Article
Incremental prognostic value of myocardial strain over ventricular volume in patients with repaired tetralogy of Fallot
The relative incremental predictive value of myocardial deformation over ventricular volume for future adverse events in patients with repaired tetralogy of Fallot (rTOF) remains unknown. We aimed to determine...
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Article
Open AccessStepwise reduction of bone mineral density increases the risk of cage subsidence in oblique lumbar interbody fusion patients biomechanically: an in-silico study
Cage subsidence causes poor prognoses in patients treated by oblique lumbar interbody fusion (OLIF). Deterioration of the biomechanical environment initially triggers cage subsidence, and patients with low bon...
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Article
Cardiac magnetic resonance T1 map** for evaluating myocardial fibrosis in patients with type 2 diabetes mellitus: correlation with left ventricular longitudinal diastolic dysfunction
We aimed to evaluate myocardial fibrosis using cardiac magnetic resonance (CMR) T1 map** in type 2 diabetes mellitus (T2DM) patients and investigate the association between left ventricular (LV) subclinical ...
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Myocardial microvascular function assessed by CMR first-pass perfusion in patients treated with chemotherapy for gynecologic malignancies
Cancer chemotherapy potentially increases the risk of myocardial ischemia. This study assessed myocardial microvascular function by cardiac magnetic resonance (CMR) first-pass perfusion in patients treated wit...
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Article
A comprehensive prognostic analysis of osimertinib treatment in advanced non-small cell lung cancer patients with acquired EGFR-T790M mutation: a real-world study
Osimertinib is the standard treatment for advanced non-small cell lung cancer (NSCLC) patients with T790M mutation after the failure of first-/second-generation epidermal growth factor receptor tyrosine kinase...
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Open AccessTexture analysis of T2-weighted cardiovascular magnetic resonance imaging to discriminate between cardiac amyloidosis and hypertrophic cardiomyopathy
To elucidate the value of texture analysis (TA) in detecting and differentiating myocardial tissue alterations on T2-weighted CMR (cardiovascular magnetic resonance imaging) in patients with cardiac amyloidosi...
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Article
Open AccessLearning to predict in-hospital mortality risk in the intensive care unit with attention-based temporal convolution network
Dynamic prediction of patient mortality risk in the ICU with time series data is limited due to high dimensionality, uncertainty in sampling intervals, and other issues. A new deep learning method, temporal co...
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Open AccessA randomized controlled clinical trial of prolonged balloon inflation during stent deployment strategy in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a pilot study
Primary percutaneous coronary intervention (PPCI) is the standard procedure for reperfusion for ST-segment elevation myocardial infarction (STEMI), but the occurrence of the no-reflow phenomenon remains common...
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Long-term outcomes and prognostic factors in papillary thyroid microcarcinoma patients with distant metastases
Distant metastasis from papillary thyroid microcarcinoma (PTMC) is extremely rare and the long-term outcomes and independent prognostic factors remain unclear. The present study aimed to investigate clinicopat...
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Article
High-dimensional and single-cell transcriptome analysis of the tumor microenvironment in angioimmunoblastic T cell lymphoma (AITL)
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive lymphoid malignancy associated with a poor clinical prognosis. The AITL tumor microenvironment (TME) is unique, featuring a minority population of mal...
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Article
A CT-based radiomics nomogram for differentiation of squamous cell carcinoma and non-Hodgkin’s lymphoma of the palatine tonsil
Accurate preoperative differentiation between squamous cell carcinoma (SCC) and non-Hodgkin’s lymphoma (NHL) in the palatine tonsil is crucial because of their different treatment. This study aimed to construc...
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Article
Increased oxygenation is associated with myocardial inflammation and adverse regional remodeling after acute ST-segment elevation myocardial infarction
To explore the relationships between oxygenation signal intensity (SI) with myocardial inflammation and regional left ventricular (LV) remodeling in reperfused acute ST-segment elevation myocardial infarction ...
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Open AccessGiant cell tumors of the mobile spine with invasion of adjacent vertebrae: an unusual imaging finding
Giant cell tumors of the mobile spine invasion of the adjacent vertebrae are an ignored imaging finding.